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Posts by Radovan Sebesta

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Recent Advances in Mechanochemical Metal-Catalyzed Cross-Coupling Reactions Cross-coupling reactions are key chemical transformations allowing efficient construction of structurally diverse molecules. This review surveys recen…

I am happy to share our review on recent advances in mechanochemical metal-catalyzed cross-couplings sciencedirect.com/science/arti...
Dr. Suman Yadav, @comeniusuni.bsky.social

3 weeks ago 2 0 0 0
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Did you see Franziska Emmerling's Editor's pick? This collection contains some of her favourite RSC Mechanochemistry articles published to date.

Read the collection for free: pubs.rsc.org/en/journals/...

2 months ago 1 1 0 0
Thieme E-Journals - Synthesis / Abstract Thieme E-Books & E-Journals

Quisqualic acid is an interesting non-proteinogenic amino acid with applications in medicinal chemistry. Have a look at our detailed account on its synthesis, which was just published in Synthesis @synthesis1969.bsky.social
www.thieme-connect.de/products/ejo...

3 months ago 3 1 0 0
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Writing is thinking

"On the value of human-generated scientific writing in the age of large-language models."

www.nature.com/articles/s44...

3 months ago 180 60 4 5
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Magnetically bistable Co(II) and Fe(II) complexes featuring pentyl-decorated pyridyl-benzimidazole ligands: role of isomerism and chirality Three variants of 2-(pyridine-2-yl)-1H-benzimidazole bidentate ligands, with distinct pentyl substituents (n-pentyl (L1), (2S)-2-methylbutyl (L2S), and (2R)-2-methylbutyl (L2R)), were synthesized and ...

I am glad that we could contribute to this interesting project led by prof. Ivan Salitros on magnetically bistable Co(ii) and Fe(ii) complexes published in Inorganic Chemistry Frontiers
pubs.rsc.org/en/content/a...

4 months ago 4 0 0 0
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Mechanochemical Stereoselective Povarov Reaction via Brønsted Acid Organocatalysis Mechanochemical activation enables the synthesis of chiral tetrahydroquinolines with excellent enantioselectivity and good yield. This asymmetric Povarov reaction is efficiently catalyzed via BINOL-b...

We report here that Povarov cycloaddition is highly enantioselective under mechanochemical conditions using chiral Bronsted acid catalysts - Chemistry – A European Journal - chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
P. Kisszekelyi, T. Doblejova, E. Rakovsky
@comeniusuni.bsky.social

5 months ago 2 0 0 0
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One‐Pot Synthesis of Ferrocene Thioamides from Ferrocenecarboxaldehyde via the Willgerodt–Kindler Reaction A series of ferrocene thioamides is synthesized via Willgerodt–Kindler reaction from ferrocenecarboxaldehyde. Two experimental protocols are developed to effectively employ both primary and secondary...

We have been overcome by our passion for ferrocene and had to make some beautiful ferrocene thioamides via Willgerodt–Kindler Reaction - Eur. J. Org. Chem. - chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
@comeniusuni.bsky.social
H. Kabzan, P. Kisszekelyi, J. Filo, M, Cigan, E. Rakovsky

5 months ago 1 0 0 0
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Chemical Papers Chemical Papers® is a peer-reviewed journal focusing on basic and applied chemistry and chemical engineering research. Covers a large scope including ...

New issue (Issue 10, October 2025) of
#ChemicalPapers (part of Springer Nature
family) is now online with 59 interesting papers across various chemistry topics.
link.springer.com/journal/1169...

6 months ago 2 0 0 0
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Spreading the word that mechanochemistry is great for metal catalyzed cross-couplings and carbonylations at 77. Meeting of chemists in High Tatras

7 months ago 3 0 0 0
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I am proud to present three new doctors from our group: Dr. Henrich Szabados, Dr. Barbora Zahradnikova, and Dr. Klara Stankovianska.
@comeniusuni.bsky.social

7 months ago 1 0 0 0
Atroposelective organocatalytic synthesis of 1,2'-binaphthalene-3'-carbaldehydes under mechanochemical conditions Ball-milling allowed the efficient realization of asymmetric organocatalytic Michael/aldol cascade, which affords 1',2´-dihydro-1,2´-binaphthalene derivatives. These compounds were transformed into ax...

Our newest example of catalytic mechanochemistry - atroposelective organocatalytic synthesis of 1,2'-binaphthalene-3'-carbaldehydes under mechanochemical conditions - now published in RSC Mechanochemistry
@comeniusuni.bsky.social, with Henrich Szabados
doi.org/10.1039/D5MR...

8 months ago 0 0 0 0

I played the Leningrad variation of the Dutch defense.

9 months ago 2 0 1 0
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I always love returning to Switzerland. This time to attend #EuCOMC2025 in Bern and speak about mechanochemical cross-couplings.

9 months ago 1 0 0 0
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Cordial congratulations to our PhD student Zuzana Mravíková for receiving Dean´s award for the best publication of PhD students for her work published in ChemSusChem 2025, 18, e202402599 (lnkd.in/eWDu5ppB)

10 months ago 1 0 0 0
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I cordially welcome our new postdoc, Dr. Suman Yadav, have a good time in research group.

11 months ago 3 0 0 0

Yes, arrows are a fascinating topic 😃

11 months ago 0 0 0 0
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The thematic issue “Advances in asymmetric #organocatalysis II” ed. by Radovan Šebesta @rsebesta.bsky.social, @comeniusuni.bsky.social, in the Beilstein Journal of Organic Chemistry is complete ➡️ https://tinyurl.com/yc24a85y
#GreenChemistry #greensolvents #catalysis #DiamondOpenAccess 💎🔓 #BJOC

11 months ago 4 1 0 0
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Outstanding peer reviewers | Royal Society of Chemistry Thank you to each and every one of our peer reviewers working tirelessly to ensure that the scientific record is accurate and getting great science into the world.

I am happy to share that I’ve been recognised as one of the Royal Society of Chemistry’s 2024 outstanding reviewers for @chemcomm.rsc.org . Explore the full list at rsc.li/OutstandingReviewers2024 #RSCPeerReview

11 months ago 4 0 0 0
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Mechanochemical Radical Boronation of Aryl Diazonium Salts Promoted by Sodium Chloride Mechanochemically performed boronation of arene diazonium salts is presented. The key feature of this method is NaCl which significantly enhances this procedure. Mechanistic and DFT investigations su...

It is nice to learn that our work is read. Our article received enough views to be a Top Viewed Article. Read it here onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle
@wiley.com

1 year ago 1 0 0 0

Our chapter "Partial Reduction of Enones, Styrenes, and Related Systems" for the upcoming release of Comprehensive Organic Synthesis is published
doi.org/10.1016/B978...
With Dr. Viktoria Nemethova, @comeniusuni.bsky.social

1 year ago 1 0 0 0
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Pd‐Catalyzed Cross‐Coupling of Organozinc Pivalates with Arene Thianthrenium Salts under Ball‐milling Conditions Cross-coupling reactions are important tools in the synthesis of complex molecules. Here we show that the Pd-catalyzed cross-coupling of aryl zinc pivalates with aryl thianthrenium salts offers a gre...

Mechanochemistry and organometallics - Pd-catalyzed coupling of organozinc pivalates and arene thianthrenium salts go well together as can be seen in our recent work
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
@comeniusuni.bsky.social, T. Carny, M. Mart, M. Blauciak, B. Steinhublova.

1 year ago 4 1 1 0
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Reunion with past and present group members at the occasion of my 20 years at Comenius University

1 year ago 2 0 0 0

🧪Here are our current open positions:
www.benferinga.com/vacancies/

- PhD on Functional DNA-Rotator Motors
- PhD in the Origin of Homochirality
- PhD on Expanding Prebiotic Chemistry Through Reactivity in Oil Droplets
- Postdoc Molecular motors based DNA-walkers

1 year ago 8 5 0 1
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📢 PhD position is open in my group starting in october 2025 for 3-years.
MSc. 👨‍🎓 interested in environmental chemistry; it is time to apply for exciting science at #PC2A @univlille.bsky.social @cnrs-hautsdefrance.bsky.social
@ph15.bsky.social @arizonastateuni.bsky.social
deadline: april 25th 2025

1 year ago 4 1 0 1
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Mechanochemical Palladium‐catalyzed Cross‐coupling of Thianthrenium Salts and Arylboronic Acids Cross-coupling reactions are indispensable for the construction of complex molecular scaffolds. In this work, we developed a sustainable methodology for the cross-coupling reaction of arene thianthre...

Another product of our passion for catalytic mechanochemistry - Suzuki-type cross-coupling with thianthrenium salts #ChemSusChem, #Mechanochemistry
doi.org/10.1002/cssc...
@comeniusuni.bsky.social
Zuzana Mravikova, Tibor Penaska, Daniela Horniakova

1 year ago 4 1 1 0
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Recent advances in organocatalytic atroposelective reactions Beilstein Journal of Organic Chemistry

If you are interested in asymmetric organocatalysis and axially chiral compounds, check out our recent review in Beilstein J. Org. Chem. Chem.
www.beilstein-journals.org/bjoc/article...

1 year ago 5 2 0 0
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Utilizing N‐Hydroxylamine‐Based Active Esters for the Synthesis of Oseltamivir Amide Derivatives Hydroxylamine-derived active esters were synthesized from oseltamivir, which can serve as practical synthetic handles to prepare oseltamivir analogs. Succinimide-based active ester was the most effec...

If you are interested in how to make carboxamide derivatives of oseltamivir, check out our recent article in EurJOC chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

1 year ago 4 1 0 0
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Mechanochemical Pd‐Catalyzed Cross‐Coupling of In‐Situ Generated Reformatsky Zn‐Enolates Transition-metal-catalyzed α-arylations of carbonyl compounds have shown to be a useful strategy for the late-stage synthesis of α-arylesters. However, the use of strong basic conditions and difficul...

I present our newest work on mechanochemical cross-couplings of Reformatsky enolates with aryl halides, which has been published in Advanced Synthesis and Catalysis onlinelibrary.wiley.com/doi/10.1002/...

1 year ago 2 0 0 0
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Our new toy for mechanochemistry! We believe chemical reactions should be shaken, not stirred. :D

1 year ago 4 0 0 0