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Posts by Pavel Dimens

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[ANN] BioToolkit.jl: A high-performance biocomputing package - #5 by kevbonham - Package Announcements - Julia Programming Language It’s great to have more people doing biology with julia! Some of the rest of this post may seem like criticism, so I want to say up front that it’s not - julia is a great language for people that like to “roll their own”, and you are welcome to find value wherever you like. That said, it would also be useful to have a discussion about the limitations that you found in the rest of the ecosystem, and if you’ve truly found performance benefits, how we might share those with the rest of the communi...

Kudos to KB for his incredible diplomacy and promoting the kindness and openness of the Julia community when all I want to say is significantly less cordial and diplomatic.
discourse.julialang.org/t/ann-biotoo...

1 week ago 0 0 0 0

And it's unsurprisingly bad. And the 'effort' feels like a dismissal of the hours/years/months I and the other developers spent learning the math, computer science things, etc., before implementing it all.

1 week ago 0 0 1 0

Well, AI slop finally became personal. A (presumably) well-meaning person outside of biology decided to reimplement all of the highly optimized and specialized packages in BioJulia into a single package using AI.

1 week ago 0 0 1 0
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A be-floor and after of what I've been doing when I come home from work

5 months ago 0 0 0 0
AToUT – TIRIS – Toulouse's Science In and For Society

Fifteen 2-year postdoc fellowships available at U. Toulouse 😍 through a MSCA-COFUND (AToUT tiris.univ-toulouse.fr/en/programs/...)

Interested to apply for a postdoctoral research project focusing on the genomics of farm animals or pollinators? Let me know!

Eligibility: <1 yr in 🇫🇷 in the last 3 yrs

7 months ago 4 9 1 0
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2025 - Hypoxia PhD job ad The Moore lab at the University of Colorado Denver is searching for 1 Ph.D. student to study the elevational limits of dragonflies in Colorado (http://moore-evo-eco.weebly.com). This position is fully...

Are you looking for a PhD position and want to spend your summers in the Rocky Mountains?

My lab @cudenverclas.bsky.social is looking for 1 PhD student to work on a NSF-funded project to study elevational range shifts in Colorado! 🧪🌍🐙

Apply by Nov 1!

Details here docs.google.com/document/d/1...

8 months ago 34 35 3 3

Nooooo. I learned the hard way that you have to wash with cold/cool water bc warm/hot opens up the pores and the skin drinks the stink in. The smell lingered for a month at least :(

6 months ago 1 0 0 0
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A 12-foot statue of Donald Trump and Jeffrey Epstein frolicking and holding hands appeared on the National Mall in Washington, DC on Tuesday, September 23.

A plaque under the statue states that it has been erected “In Honor of Friendship Month."

6 months ago 6884 2333 226 323
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GitHub - pdimens/djinn: Convert linked-read FASTQ/BAM files between formats, like magic. Convert linked-read FASTQ/BAM files between formats, like magic. - pdimens/djinn

I didn't love how monolithic Harpy was becoming with novel features. So, the file-modification things were split out into Djinn. So, use Djinn if you need to convert linked-read fastq/bams
#bioinformatics
github.com/pdimens/djin...

6 months ago 0 0 0 0

Band Name Idea;
Blood Bath & Beyond

Debut Album:
Bath Salts

7 months ago 0 0 0 0
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Hi, I’m Julie Cruse. I created AcademicAbuse.com – a dashboard of data, resources & tools to help survivors of academic abuse survive and safely speak out. (1/9 🧵)

🪜 🎓 📜 🍎 ♀️ 👩🏾🔬 👩🏼🔬 👩🏾🎓 #PhDSky #Blackademia #AcademicChatter #AcademicSky #MeToo #HigherEd #PhDChat #TimesUpHigherEd

7 months ago 28 21 3 0

Since finishing my PhD in 2022 I have:
1. Rediscovered my belly laugh
2. Cried at my first wedding

Hard to describe how powerful it is to acknowledge healing.

7 months ago 0 0 0 0
GitHub - pdimens/harpy: Process linked-read data, from raw sequences to phased haplotypes, batteries included. Works with WGS too! Process linked-read data, from raw sequences to phased haplotypes, batteries included. Works with WGS too! - pdimens/harpy

And the link, if you're into that sort of thing:
github.com/pdimens/harpy

7 months ago 0 0 0 0
The software logo, text that reads "Harpy" and a badge beside the text that indicates it's version 3.0

The software logo, text that reads "Harpy" and a badge beside the text that indicates it's version 3.0

My lil' baby turns 3.0 today! Most notable features:
- autodetection of linked-read types (and not linked-read WGS too!)
- more debuggin' and troubleshootin' options

#bioinformatics #genomics #linkedreads

7 months ago 3 3 1 0
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I'm looking to recruit a PhD student to study patterns of local adaptation and introgression across the spruce hybrid zone in the Rockies near Calgary. Projects can include field work, bioinformatics, pop gen theory, or comparison to plant/ conifer species
yeamanlab.weebly.com/uploads/5/7/...

8 months ago 66 75 2 2
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Real betrayal with how that PNG was rendered. Here's the actual logo

8 months ago 0 0 0 0
A logo featuring the word "Arachne", where the "h" is depicted as a half-spider humanoid knitting what looks like DNA

A logo featuring the word "Arachne", where the "h" is depicted as a half-spider humanoid knitting what looks like DNA

Today, that Go project *finally compiled*! It only took 7 complete project restructuring attempts. Now that it builds, the real work begins, and it's a good time to reveal I'm trying to revive Lariat, the linked-read aligner written by 10X Genomics. It's called Arachne 😁🕷️ github.com/pdimens/arac...

8 months ago 1 1 1 0

I'm trying to revive an abandoned #bioinformatics software written Go. I have no experience with Go (or similar langs), but doing my best. Does anyone here have even middling experience with Go that can lend some wisdom or time towards this effort?

8 months ago 1 1 0 0
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Quit Yer Mouthbreathing–The open cup – Apple Podcasts Podcast Episode · The open cup · 15/08/2025 · 21m

There's a coffee tasting podcast and ya boi has a guest spot on it this week cupping Don't Be Alarmed by Coffeemania. Y'all should give their stuff a listen ☕
podcasts.apple.com/gb/podcast/q...

8 months ago 1 0 0 0

This morning, my sister told me that they're making The Mask 3 and I've been stressed ever since.

8 months ago 1 0 0 0
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Can confirm-- I feel smug af

8 months ago 1 0 0 0

In the year of our lord 2025, I don't see why `scale_color_brewer()` is still case sensitive for the color palette

8 months ago 2 0 0 0

Out of necessity, I've recently got into reviving abandoned/dead linked-read bioinformatics software. Can be seen as software necromancy or adoption, depending on what you consider abandonware. I prefer calling it necromancy, tbh.

8 months ago 3 0 0 0

"How hard can it be?" he thought to himself before taking on another time-sucking project he is grossly unqualified to have even considered.

Anyway, if this works, expect another linked read software with another monster/creature name 🐉

8 months ago 1 0 0 0
A minimal cartoon of a treasure chest with teeth, featuring three circles in a triangle as an "eye"

A minimal cartoon of a treasure chest with teeth, featuring three circles in a triangle as an "eye"

The Mimick logo has been updated to reflect its new #julialang codebase 👀🙌

9 months ago 5 1 0 0
A series of failed continuous integration tests trying to introduce a new feature. The topmost test, titled "I guess we can't have nice things" is the only one that succeeded.

A series of failed continuous integration tests trying to introduce a new feature. The topmost test, titled "I guess we can't have nice things" is the only one that succeeded.

If you've ever wondered how the sausage gets made over here in Harpy land, behold

9 months ago 1 0 0 0

Been writing in #Julialang again and BOY does it feel good. 😌

9 months ago 6 0 0 0
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b/c accountability
7hrs to get these 20sec mostly up to speed. Helluva conversion ratio.

9 months ago 0 0 0 0

The world is crazy, still. Writing anything at all on social media feels stupid. But, I started learning to play Jake E. Lee's solo from Bark at the Moon and I guess I'm writing it here to 1. still somehow interact with the world and 2. foolishly hold myself accountable 🎸

9 months ago 2 0 1 0
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GitHub - pdimens/mimick: Linked-read sequence simulator Linked-read sequence simulator. Contribute to pdimens/mimick development by creating an account on GitHub.

Mimick now works with circular DNA, far all you microbial linked-read enthusiasts 🦠🧬

Go out and simulate you some data 💪

github.com/pdimens/mimick

9 months ago 1 0 0 0