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Posts by Alex Costa

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There is still time to register for the EMBO Workshop on Plant Calcium Signaling 2026!

Dive into cutting-edge research on Ca²⁺ signaling in plants 🌿

Primosten, Croatia | 20–24 Sept 2026

meetings.embo.org/event/26-cal...

Travel grants are available

embo.org/funding/lect...

4 days ago 2 3 0 0
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In Vivo Monitoring of Energy Metabolism with Genetically Encoded Fluorescent Biosensors All organisms fuel and build themselves through their energy metabolism. While classic biochemistry conceptualizes the fluxes of energy and matter, our understanding of how energy metabolism works in ...

In Vivo Monitoring of Energy Metabolism with Genetically Encoded Fluorescent Biosensors - www.annualreviews.org/content/jour...

1 month ago 3 2 0 0

Many thanks to @plantaeofficial.bsky.social for having highlighted our work...

1 month ago 2 0 0 0
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Macro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging | Plantae The bid to understand long distance Ca2+ signaling patterns in co-ordinating whole-plant responses to systemic or induced defense have been scarce in soil-grown plants mainly due to limitations of…

Plant Science Research Weekly --  Macro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging (Science Advances) @labcosta.bsky.social (Summary by Indrani Kakati @indranik18.bsky.social) buff.ly/LxaRjzT

#PlantaePSRW

1 month ago 8 5 1 0
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With MAPPI, we can design simple fluorescent experiments for long-term Ca²⁺ imaging — 16 hours in this video — tracking signals (if any) during growth or dynamic movements 📷

@ScienceAdvances @science.org

science.org/doi/10.1126/...

1 month ago 0 0 0 0
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Visualizing how a plant's leaves, stem and roots mutually communicate under environmental stress in real time How do the different parts of an adult plant communicate with each other when it suffers an injury, is waterlogged, burnt or exposed to environmental stress? Today we can answer this question thanks t...

phys.org/news/2026-02...

2 months ago 10 3 0 0
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Plants "talk" internally — and now we can watch it happen.

MAPPI lets us track shoot-to-root Ca²⁺ signals in real time 🌱⚡

@ScienceAdvance! @science.org

science.org/doi/10.1126/...

2 months ago 17 5 1 0
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Explore plant #CalciumSignaling in the eponymous EMBO Workshop "Plant calcium signaling" in #Primosten, Croatia, 20–24 September 2026.

Abstract submission deadline: 1 May
Registration deadline: 31 May

https://meetings.embo.org/event/26-calcium-signaling
#EMBOCalciumSignaling #EMBOevents 🧪

2 months ago 9 5 0 0
Video

@ScienceAdvances @science.org

Using MAPPI for real-time whole-plant imaging, we reveal the earliest flooding response — a Ca²⁺ signal, expected, yet now directly visualised and strongest in young leaves...🔬📷

science.org/doi/10.1126/...

2 months ago 9 3 0 0
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We thank Jon K. Pittman for his thoughtful and inspiring commentary

nph.onlinelibrary.wiley.com/doi/10.1111/...

published in @newphyt.bsky.social

on our recent work (Grenzi et al. 2025)

nph.onlinelibrary.wiley.com/doi/10.1111/...

2 months ago 5 2 0 0

Thanks!

2 months ago 1 0 0 0
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🔥 Spodoptera littoralis feeding doesn’t just spike cytosolic Ca²⁺ — it also unleashes a surge of apoplastic glutamate in Nicotiana benthamiana

@ScienceAdvances

science.org/doi/10.1126/...

2 months ago 4 1 1 0
Video

Registration is now OPEN for the EMBO Workshop on Plant Calcium Signaling 2026!

Dive into cutting-edge research on Ca²⁺ signaling in plants 🌿

📍 Primosten, Croatia | 🗓️ 20–24 September 2026

meetings.embo.org/event/26-cal...

2 months ago 3 1 0 0
Video

The MAPPI setup we @AndreaBassi78 @labcosta.bsky.social
published in @ScienceAdvances shows its versatility, enabling us to design amazing experiments that we never thought could be possible...

science.org/doi/10.1126/...

So, now guess what this video is showing❔❔

2 months ago 7 2 0 0

Hi Jim...we think that we are a community and we need to share our results...this is what I consider Advances...a technology that many people can use...

2 months ago 1 0 0 0

Yes, we have built it in my lab...if you read the paper you can have an idea about the many possibilities it offers...

2 months ago 1 0 1 0

Many thanks Stephan...

2 months ago 1 0 0 0
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@labcosta.bsky.social Out now in ScienceAdvances
our new work with @AndreaBassi78

MAcro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging | Science Advances science.org/doi/10.1126/...

2 months ago 30 17 3 1
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🚀 New Review out by @elenist.bsky.social @labcosta.bsky.social
Bioelectronics for basic plant science and precision agriculture 🌱⚡️
A deep dive into how bioelectronic tools are transforming plant research & farming...
Published in Nature Reviews Electrical Engineering: doi.org/10.1038/s442...

3 months ago 0 0 0 0
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Huge thanks to @Nikon for an unforgettable Christmas present 🎁 Feeling truly privileged to receive such a unique microscope 🔬

3 months ago 11 1 1 0
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Small molecule, big impact: H2S contributes to pathogen-induced stomatal closure Plants are sessile organisms and must integrate information from a range of external stimuli to respond appropriately to their environment. Stomata form a

Small molecule, big impact: H2S contributes to pathogen-induced stomatal closure url: academic.oup.com/plphys/artic...

Really nice News & Views on the new paper from @charliemdq.bsky.social’s lab 👏

academic.oup.com/plphys/artic...

3 months ago 14 4 0 0
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Hydrogen sulfide modulates flagellin-induced stomatal immunity Hydrogen sulfide and L-CYSTEINE DESULFHYDRASE1 actively participate in flagellin-induced stomatal closure, modulating apoplastic and cytosolic reactive oxy

Just for Xmas! Nice collaboration with @schwarzlanderlab.bsky.social and @labcosta.bsky.social labs.

Hydrogen sulfide modulates flagellin-induced stomatal immunity url: academic.oup.com/plphys/artic...

3 months ago 7 2 0 0
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Hydrogen sulfide modulates flagellin-induced stomatal immunity Hydrogen sulfide and L-CYSTEINE DESULFHYDRASE1 actively participate in flagellin-induced stomatal closure, modulating apoplastic and cytosolic reactive oxy

Great collaboration with @Charlie Garcia-Mata lab!

🧪 New Plant Physiology paper: Hydrogen sulfide modulates flagellin-induced stomatal immunity, revealing a key role for H₂S in guard cell immune responses 🌱

academic.oup.com/plphys/artic...

3 months ago 7 2 1 0
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Subfamily I ethylene receptors are functionally conserved in calcium permeability across the green lineage #research #MolecularPlant cell.com/molecular-pl...

3 months ago 4 2 0 0
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Merry Christmas and Happy Holidays from @labcosta.bsky.social! 🎄✨ Thanks to all our collaborators, colleagues, and friends for a great year together.

4 months ago 7 1 0 0
Pharmacological strategy to study the blue light-induced endoplasmic reticulum Ca2+ depletion and its coupling to cytosolic Ca2+ dynamics in Arabidopsis guard cell.

Pharmacological strategy to study the blue light-induced endoplasmic reticulum Ca2+ depletion and its coupling to cytosolic Ca2+ dynamics in Arabidopsis guard cell.

Investigating the origin of spontaneous cytosolic calcium oscillations in stomatal guard cells: a dialogue between apoplastic and endoplasmic reticulum stores

Grenzi et al. @labcosta.bsky.social

nph.onlinelibrary.wiley.com/share/KRMCPP...

4 months ago 6 1 0 0
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...we can infer that, in the presence of CPA, the ER behaves like anengine without fuel, incapable of sustaining the mechanism required to maintain the [Ca²⁺]cyt oscillations... doi.org/10.1111/nph....

4 months ago 1 0 0 0
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Blue light decreases ER Ca²⁺ in stomatal guard cells, with refilling in the dark. Our new @newphyt.bsky.social study shows how ER Ca²⁺ shapes cytosolic Ca²⁺ dynamics
doi.org/10.1111/nph....

4 months ago 31 12 0 1

Two acceptances back-to-back on plant Ca²⁺ signaling!
🌱 The ER role in guard cell Ca²⁺ signaling
@newphyt.bsky.social

🔬 A new way to perform Ca²⁺ imaging in adult plants grown under physiological conditions
Science Advances @science.org

Stay tuned — details coming soon!

4 months ago 6 0 1 0
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SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...

SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance | Science www.science.org/doi/10.1126/...

6 months ago 6 2 0 0