He’s absurd. 35 points and 5-6 from 3. Honestly don’t know how he doesn’t score on every possession.

Wow! I saw them almost 30 years ago at Red Rocks with Social D, L7 and Offspring. Awesome that they’re still going strong.

Massive Attack, Tom Waits - Boots on the Ground YouTube video by Massive Attack

They just dropped a music video/documentary:

www.youtube.com/watch?v=L-57...

Sex effects on gene expression across the human cerebral cortex at cell type resolution Sex differences in neurodevelopmental, psychiatric, and neurodegenerative disease susceptibility may arise from sex chromosome and hormonal influences on cell type–specific gene expression. We present...

My sister’s new article in Science!!! Congrats 🎉 @coevolvinglab.bsky.social

Sex effects on gene expression across the human cerebral cortex at cell type resolution | Science www.science.org/doi/10.1126/...

New preprint!
"A stereotyped glial attachment determines the morphology and function of neuronal cilia"
doi.org/10.64898/202...

We find that C. elegans neuronal cilia attach to glia, we identify a protein required for cilia-glia attachment, and we show that glial attachments alter cilia signaling.

Congrats to the newest PhD from the @siegenthalerlab.bsky.social, Dr. Sophia Kim! Beautiful thesis document & presentation! 🧠🦠🔬🎉

Sophia's thesis work on arachnoid barrier breakdown in meningitis is on bioRxiv - check it out!
www.biorxiv.org/content/10.6...

Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair - Nature The transcription factor ATF4 is shown to regulate double-stranded DNA repair within vulnerable CUX2+ upper-layer 2/3 cortical neurons, enabling their survival during development.

Two very cool papers out in Nature from the labs of Stephen Fancy and David Rowitch.

In one study they show that the developmental expansion of CUX2+ neocortical neuron progenitors requires enhanced DNA repair mechanisms to deal with replicative stress.

1/4

www.nature.com/articles/s41...

You’re right, this was probably the intent. I think I was just confused because these instructions came during the review phase, prior to read phase. Most likely they meant adjust score during read phase to rescue, as you point out.

I read the instructions to mean there is no rescuing at all, even prior to review day. Only "preemptive rescuing" by giving apps a score of 1 to automatically trigger discussion. But it's impossible to know ahead of time if an app will need rescuing. I have to see the other critiques first.

These instructions were new to me this time around: "Your request to bring an application up for discussion from a not-to-be discussed list cannot be accepted at this meeting, so please give a score of 1 now if you think it is truly outstanding and insist on discussing it."

Happy to have played a very small part in these studies and thankful to the Fancy & Rowitch Labs for including us.

Congrats to Laura Morcom, Wenlong Xia, and everyone involved!

4/4

Fate-Restricted Neural Progenitors in the Mammalian Cerebral Cortex Where cortical neurons end up is determined before they begin to move.

These studies add an interesting new angle to our 2012 paper on Cux2+ progenitors, showing that they are not only a distinct lineage but also have specific molecular mechanisms to deal with selective vulnerabilities in development and disease.

3/4

www.science.org/doi/10.1126/...

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation - Nature DNA damage burden and inadequate repair in CUX2+ cortical layer 2/3 excitatory neurons contributes to selective vulnerability in neuroinflammatory injury.

In the companion study they show that these CUX2+ neurons are selectively vulnerable to degeneration in models of MS and neuroinflammation, and the enhanced DNA repair mechanisms are required to promote resilience during neuroinflammation.

2/4

www.nature.com/articles/s41...

Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair - Nature The transcription factor ATF4 is shown to regulate double-stranded DNA repair within vulnerable CUX2+ upper-layer 2/3 cortical neurons, enabling their survival during development.

Two very cool papers out in Nature from the labs of Stephen Fancy and David Rowitch.

In one study they show that the developmental expansion of CUX2+ neocortical neuron progenitors requires enhanced DNA repair mechanisms to deal with replicative stress.

1/4

www.nature.com/articles/s41...

Flexible ensheathment of axons enables myelination of complex CNS networks - Nature The rate of axon ensheathment varies within individual myelinating processes, resulting in chains of myelin sheaths connected by bridges consisting of thin cytoplasmic processes that provide&nbsp...

Latest offering. How myelin ensheathes axons!

Born from chat with Dwight Bergles on "weird things" we saw oligodendrocytes do, like making "bridges" between sheaths.

Driven forward by Cody Call, Kelly Monk, and myelin folks @edinburgh-uni.bsky.social

Enjoy!
www.nature.com/articles/s41...

Neurogenesis and Repair 2026 Join Neurogenesis and Repair 2026, July 13-16, 2026. Learn more on Fourwaves.

Neurogenesis meeting in Toronto 🇨🇦 on July 13-16. Great line up of speakers.

If I knew what I know now in graduate school I wouldn't have audited Kant's first Critique like three times and would've replaced at least one of those with a class about making Canvas modules because my job has way less first Critique and way more making Canvas modules than I could've ever guessed.

The biggest thing I have to explain to normal friends is that I basically have 2 chances for raises over the lifetime of my career (promotion to Associate and promotion to Full). Beyond that, you generally have to have an offer from another university to change your compensation (not a guarantee).

Roswell saw its earliest 100° day on record today, breaking the old record by almost a month. This is the first time they have seen a 100° day during the month of March. #NMwx

Today in Nature Neuroscience we have published our exploration of neocortical development leveraging 100's of public datasets. You can interrogate the entire compendium of data at nemoanalytics.org/landing/neoc... and read the paper at www.nature.com/articles/s41....

Sujatha Jagannathan from the University of Colorado Anschutz School of Medicine is next to take the floor in the first session. Her talk is focused on mapping of nonsense-mediated mRNA decay.

#VariantEffect26
#NMD #Mapping
#AtlasOfVariantEffectsAlliance

NIH Fellowship awards for FY2025 by race The NIH Data Book page reporting Research Project Grants (RPG) and Fellowship awards by race has been updated for FY2025. Completely unsurprisingly, despite the impression that may have been convey…

NIH Fellowship awards for FY2025 by race drugmonkey.wordpress.com/2026/03/19/n...

NIH Fellowship awards for FY2025 by ethnicity The NIH Data Book page reporting Research Project Grants (RPG) and Fellowship awards by ethnicity has been updated for FY2025. From this page we can look at the impact of FY2025 chaos on the fundin…

NIH Fellowship awards for FY2025 by ethnicity drugmonkey.wordpress.com/2026/03/23/n...

"The other way to put this is that NIH funded 33.1% fewer Hispanic trainees and only 6.3% fewer Non-Hispanic trainees in FY2025...we probably don’t have to think about this too deeply. The anti 'DEI' agenda of the new regime...is probably sufficient"

Delighted to share that our study is now out @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce... Congrats to Dr. @federicamosti.bsky.social for the culmination of a beautiful thesis!

Submit to our Developmental Biology Special Issue - Receptor tyrosine kinase signaling in development!😎

Guest editors
Katherine Fantauzzo @fantauzzolab.bsky.social
Jennifer Fish

Deadline April 30th, 2026

@socdevbio.bsky.social

Linked here👇
www.sciencedirect.com/special-issu...

2027 Neuroimmune Gordon Research Conference - Jan 24-29, 2027👇 www.grc.org/neuroimmune-...

Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs - Nature Neuroscience Single-nucleus epigenomic maps of the adult human brain and spinal cord reveal that adult oligodendroglia retain developmental chromatin patterns, suggesting a molecular memory that may shape repair p...

Our latest in @natneuro.nature.com, lead by Mukund Kabbe, providing single cell epigenomic maps of the human brain and spinal cord with snATAC and our NanoCUT&Tag and finding epigenetic memory in oligodendroglia of developmental programs!

www.nature.com/articles/s41...

Adaptive evolution of gene regulatory networks in mammalian neocortex - Nature The excitatory neuron diversity and specialized connectivity of complex, multilayered mammalian neocortex are driven by mammalian-specific cis-regulatory elements bound by ZBTB18, deletion of which di...

Happy to share my co-first-author paper, now published in Nature! In this work, we uncover gene regulatory networks that underlie the diversification and connectivity of excitatory neurons in the neocortex.

www.nature.com/articles/s41...