Are you ready to kick-off #IMMUNOLOGY2026 ?
The VectorBuilder team is excited to join the American Association of Immunologists (aai.org) at their annual IMMUNOLOGY conference in Boston.
🗓️ April 15-19, 2026
📍Booth 427 - Thomas M. Menio Convention & Exhibition Center Hall A
Will you be at the @asgct.bsky.social Annual Meeting? Join us at the Tools and Technology Forum, where Dr. Bruce Lahn will present “From Research to Clinic: A Practical Guide to Optimizing Therapeutic Vector Design.”
MuteFree™ AAV preserves ITR integrity through optimized plasmid design, enabling consistent, high-fidelity AAV production within standard workflows. By improving stability at the source, it supports more reliable and scalable gene therapy manufacturing.
ITR mutations, found in ~40% of AAV transfer plasmids, can reduce yield, introduce variability, and impact therapeutic performance.
Our new preprint introduces MuteFree™ AAV, a high-stability vector system designed to address ITR instability, a common challenge in gene therapy development. The manuscript is now available on bioRxiv. www.biorxiv.org/content/10.6...
VectorBuilder is pleased to exhibit at British Society for Gene and Cell Therapy’s Annual Conference 2026 (bsgct.bsky.social). Have a chat with Christina McClure and Tasnim Hussain to learn about our latest offerings and services for your research and therapeutic development projects.
Alzheimer’s disease develops before symptoms appear, but early brain changes are not fully understood. New work from the Misha Zilberter lab shows APOE4 drives neuronal hyperexcitability in mice and identifies Nell2 as a mediator. CRISPRi KD of Nell2 normalized activity, pointing to an early target.
For the scientists who know good science and good style go hand in hand 🧬
Coming soon… and yes, you’ll definitely want some.
Whether you need a complex vector design or a high-titer virus, we are here to help you! New and existing customers (with <3 orders) are eligible to join the innovation assembly line.
Activate your savings pass now: hubs.la/Q0483HlC0
To celebrate 12 years of VectorBuilder, we’re making it easier to get your next few projects off the ground! We’ve set up a ""Savings Roadmap"" that scales with your research:
1st Order: 20% OFF (Code: Thankyou1st)
2nd Order: 15% OFF
3rd Order: 10% OFF
Viruses deserve better PR 🦠 (cont.)
Viruses deserve better PR 🦠
Inspiration: @rspbscotland.bsky.social
Check out the full seminar here!
youtu.be/0DgvIUSo3wY
Trying to figure out if mosaic screening is right for your cancer research? Dr. James Allen, HHMI Hanna Gray Fellow & incoming faculty at Mayo Clinic, highlights mosaic screening approaches in zebrafish and its applications to discovering genetic interactions that contribute to pediatric leukemia.
Dr. @fenane.bsky.social will highlight advances in mRNA design and stability, including optimized UTRs, nucleoside modifications, and emerging modalities like sa-RNA and circ-RNA. You’ll also learn how new LNP technologies are unlocking tissue-targeted delivery!
Register now to save your spot:
mRNA is moving beyond vaccines, but where is it going next?
Join our next Gene Delivery Seminar to learn how advances in mRNA design are enabling precise, transient protein expression across diverse disease areas.
99% of grad students agree: cloning is their favorite technique.
The other 1% are still troubleshooting.
…okay fine, we made that up.
Happy April Fools’ Day! Leave the cloning to us 🧬
This April, the VectorBuilder team is heading to key conferences across the globe! 🌍
Come meet our team and learn how our research and CDMO solutions are helping accelerate breakthroughs.
HIV requires lifelong treatment to maintain viral control, driving interest in approaches that enable sustained anti-HIV antibody production. New work from Jack Castelli, PhD and the Adair lab shows CRISPR knock-in in primate HSPCs enables long-term antibody production in vivo.
Still paying for molecular biology software? VectorBee is the forever-free platform for vector design, editing, annotation, and analysis. No more paywalls, because your research deserves better!
Try VectorBee today: hubs.la/Q048fYHx0
Happening today! 🧬
Join today’s Gene Delivery Seminar to learn how you can optimize your lentiviral vectors for reliable gene delivery!
We love hearing how VectorBee is helping scientists and are constantly working to improve its features.
Check out the latest upgrades in VectorBee 3.0:
🐝https://hubs.la/Q048fYHS0
People are buzzin’ about VectorBee! 🐝
Researchers like Dr. Zubair Khalid @zubairkhalidphd.bsky.social are exploring how VectorBee can support their workflows in the lab. Our goal is to make research tools more accessible, without subscriptions, locked features, or limitations.
Going to #CDU2026? Our team will be excited to chat at CRISPR Down Under in Melbourne next week. 🧬
Stop and chat with Dr. Chee Ho H'ng (Territory Manager) to learn more about the new CRISPR and research solutions we can support for your research. See you there!
Successful gene delivery starts with choosing the right vector 🧬
Our next Gene Delivery Seminar is one week away and will focus on strategies to optimize lentiviral vector production and performance in your research.
Reserve your spot here: us06web.zoom.us/webinar/regi...
Tools like VectorBee help students visualize and apply these concepts, turning vector design into an interactive learning experience.
Download VectorBee, forever free, and start designing your own vectors: vectorbee.com/en/
🐝 What should every student learn about vector design?
In this last video, Dr. Shirley Coomber explains how VectorBee helps students understand the core elements of plasmid design, from selecting promoters to building functional expression vectors.
It was inspiring to see how VectorBee transforms vector design from a theoretical concept into an interactive learning experience.
Stay tuned for our last VectorBee in Education video, where Dr. Coomber explains the key elements students need to understand when designing vectors.
During the session, students constructed plasmids step by step while exploring biological analysis tools. They then used these skills to design an E. coli expression vector for a gene of interest before moving into the practical lab.
