Protocol-based hydration may โฌ๏ธ AKI after pulsed-field ablation for AF. In this โค๏ธ Rhythm study (n=501), AKI occurred in 6.4%; CKD, extensive LA ablation, & more PF applications increased risk. A hydration regimen (โฅ2,000 mL) โฌ๏ธ AKI risk by 67%.
๐ doi.org/10.1016/j.hr...
Posts by Rolando Claure
Great presentations & projects from the Early Career Professionals @kdigo.org meeting today #GoKDIGO
AKI e-alerts may improve recognition, but not major clinical outcomes. Xie et al.โs nationwide real-world study confirms what prior RCTs showed: no meaningful impact on mortality, progression, or recovery. More targeted strategies are needed.
๐ doi.org/10.1016/j.ki...
A short recovery๐๐ปโโ๏ธ before #KDIGO ExCom meeting ๐ #Run4Kidneys ๐ซ #850Challenge ๐๏ธ #Rome ๐ฎ๐น
The draft of @kdigo.org Clinical Practice Guideline for AKI/ AKD is now available for public review through ๐๏ธ April 27, 2026 #Nephpearls #NephSky
We invite you to review the draft and share comments to help inform the final guideline
๐ kdigo.org/guidelines/a...
Reminder: The draft of the KDIGO 2026 AKI/AKD Guideline is available for public review through Monday, April 27.
Download the guideline and submit comments via the feedback form on the guideline website: kdigo.org/guidelines/a...
Reviewers can comment on any section. All feedback is appreciated.
Listening to the patient voice ๐ฃ๏ธ matters.
Consensus conferences & clinical practice guidelines should not rely only on evidence, but also on patientsโ lived experiences, priorities, & concerns. Applause ๐๐ป to @KDIGO.org for making patient participation part of the process. #KDIGO
PPIs remain linked to important ๐ซ safety concerns ๐๐ป AKI, incident CKD, & progression to ESKD. Mechanistically, AIN appears central. Emerging data also suggest that P-CABs/vonoprazan may carry nephrotoxicity signals, comparative safety data are still evolving. #AKICRRT2026
Saturday morning at #Rome #KidneyRunners ๐ซ ๐๐ป #Run4Kidneys #850Challenge ๐๏ธ#Rome ๐ฎ๐น
In acute ๐ failure, priorities are clear: decongestion, rapid GDMT optimization, & prevention of severe AKI.
Residual congestion is not benignโit drives worse outcomes, rehospitalization, & ๐ซ complications.
#AKICRRT2026
Running ๐๐ปโโ๏ธ around the world ๐บ๏ธ today we run in 2๏ธโฃ countries and 2๏ธโฃ cities ๐๏ธ in 35 minutesโฆ Rome, ๐ฎ๐น and Vatican City , ๐ป๐ฆ #Run4Kidneys ๐ซ #850Challenge ๐๏ธ raising awareness of #KidneyDisease #KDIGO
#JustDoItSunday ๐๐ปโโ๏ธ #Run4Kidneys ๐ซ #850Challenge ๐๏ธ #Ciclovia #Cochabamba ๐ง๐ด
In hospitalized adults with SIAD and fluid restriction failure, oral NaCl plus furosemide achieved a median serum sodium correction of 1.5 mmol/L/day. Hypokalemia, hypomagnesemia, and AKI were frequent, underscoring the need for close monitoring.
๐ doi.org/10.1093/ckj/...
Point-of-care creatinine testing in a Nigerian ๐ณ๐ฌ primary care center showed a striking contrast: AKI was rare in adults (2/301) but common in children (70/123, 56.9%), especially in those <5 years old. Malaria ๐ฆ was the leading diagnosis. #AKI
๐ doi.org/10.1159/0005...
AKI doesnโt end at discharge. Survivors remain at higher risk of CKD, recurrent AKI, CV events, readmission and premature death. This review proposes 10 pragmatic tips for patient-centred post-AKI care, from early follow-up to medication optimization.
๐ doi.org/10.1093/ckj/...
Acute โฌ๏ธ in sCr are common safety end points in trials, but defining AKI is tricky: large irreversible changes may understate risk, while small reversible ones may overcall harm In ๐authors suggest MAKE90 as a default phase 3 kidney safety end point. ๐ journals.lww.com/jasn/fulltex...
#JustDoItSunday ๐๐ปโโ๏ธ #Run4Kidneys ๐ซ #850Challenge ๐๏ธ from #Cochabamba to #Tiquipaya ๐ป
The updated @kdigo.org AKI/AKD Guideline is now open for public review. Scan the QR code to read the draft and share your comments. Help shape the final guideline and improve kidney care worldwide.
#KDIGO #Guidelines #AKI #AKD
Till nextโs years @crrtonline #AKICRRT #KidneyRunners ๐๐ปโโ๏ธ #Run4Kidneys ๐ซ #850Challenge ๐๏ธ@javo_neyra
Is sex-by-age interaction a missing factor in AKI epidemiology? A ๐ of 87,087 adults found AKI in 20.6% of ๐ฅ admissions. Incidence was โฌ๏ธ in ๐ฉ๐ป overall, but worse outcomes were seen in ๐ด๐ป highlighting a dynamic interaction between sex, age, & AKI risk ๐ doi.org/10.1093/ndt/...
Sports Nephrology: A CJASN Traineesโ Spotlight highlights the growing importance of kidney health in athletes & the need to formalize Sports Nephrology through screening, kidney-focused risk assessment, & integration with sports medicine pathways. ๐ journals.lww.com/cjasn/citati...
Back to a special route in โ๏ธ #SanDiego, I ๐๐ป again @BalboaPark, the same route I used during my time as a research fellow at @ucsdnephrology. Miles full of memories that shaped my journey. Going back to where it all started is the best motivation to keep moving โก๏ธ #850Challenge ๐๏ธ #Run4Kidneys ๐ซ
A post-hoc analysis in patients with severe AKI receiving CKRT found that trajectory patterns marked by โฌ๏ธ sBUN to Cr ratio or โฌ๏ธ lactate levels were associated with especially poor outcomes. Findings were externally validated in MIMIC-IV #AKI #CKRT
๐ doi.org/10.1016/j.jc...
In a post-hoc analysis of 8,614 participants from CANVAS & CREDENCE trials, abnormal urinary leukocyte esterase & nitrite were associated with โฌ๏ธ UTI risk. Canagliflozin did not โฌ๏ธ UTI risk, including in those with abnormal urinary findings. #SGLT2i
๐ doi.org/10.1093/ndt/...
Running ๐๐ปโโ๏ธ around the ๐บ๏ธ , raising awareness of #KidneyDisease #Run4Kidneys ๐ซ #850Challenge ๐๏ธ#SanDiego ๐บ๐ธ
A narrative review doi.org/10.1093/ckj/... summarizes current evidence supporting multiparametric ๐ซ ultrasound in AKI, including B-mode imaging, arterial & venous Doppler, microvascular Doppler, & CEUS, as ๐งฐ to assess renal perfusion, congestion, & recovery. #AKI #Ultrasound
Does desmopressin reduce bleeding after kidney biopsy? In a meta-analysis of 17 trials (5,394 participants), no overall benefit was seen. IV use was linked to higher๐ฉธ odds, while SC & intranasal routes may help. Hyponatremia remains a concern. More trials needed.
๐ journals.lww.com/kidney360/ab...
Buenas noches ๐ด #KidneyRunners ๐๐ปโโ๏ธ #Run4Kidneys ๐ซ #850Challenge ๐๏ธ