Read a letter from Zach Zangl, diagnosed with ALS in 2024 and now on the board of the ALS 100, a golf event raising funds for ALS research at ALS TDI: als.net/news/l-i-v-i...
Alongside our scientists, team members like Carol are here to help you get involved in the mission.
Join us May 15 (3–4 PM ET) for an ALS Town Hall on Champions Insights. Learn how studying higher-risk groups like athletes, veterans, & first responders could help advance ALS research for everyone.
Hosted by ALS TDI, Answer ALS & Augie's Quest.
Register: als.net/als-town-hall/
We answer only to the ALS community.
That means following the science, being transparent about what we find—and what we don’t—and staying accountable to those who need answers most.
Thank you for pushing this work forward.
mRNA therapies could target multiple drivers of ALS—but delivery into the brain remains a major hurdle. ALS TDI is collaborating with Dr. Michael Mitchell (UPenn) to develop lipid nanoparticles (LNPs) to deliver these therapies: als.net/news/mrna-lnp-therapies-for-als/
Behind every experiment is a decision:
Will this bring us closer to a treatment for ALS?
At ALS TDI, we use four key questions to guide every project we take on—so we can focus on what matters most: real impact for people living with ALS. (2/2)
Behind every experiment is a decision:
Will this bring us closer to a treatment for ALS?
At ALS TDI, we use four key questions to guide every project we take on—so we can focus on what matters most: real impact for people living with ALS. (1/2)
Every data point tells a story. Every participant moves research forward.
Keith is part of the ARC Study—where participants are helping ALS TDI researchers uncover critical insights that could lead to new treatments.
Be part of it: als.net/arc
Celebrating 20 years of Shawn Sullivan at ALS TDI.
From our drug discovery pipeline to the ARC portal, ARC Data Commons, and many internal systems, Shawn’s work supports nearly every part of the Institute.
We’re incredibly grateful for his dedication.
Thank you to our 14 incredible NYC Half Marathon runners who braved the cloudy race day yesterday and ran 13.1 miles for ALS research at ALS TDI, raising $68K+.
It’s not too late to support their efforts: fundraise.als.net/donate/nychalf
Pictured here is Val caring for our zebrafish in the lab.
Zebrafish models help our scientists study ALS and test new ideas that could lead to treatments.
We take great care of every animal in our labs, and Val is the zebrafish’s most dedicated caretaker.
Join our ALS TDI Town Hall to explore The Les Turner ALS Foundation’s My ALS Decision Tool™ and ALS TDI’s ALS Trial Navigator — empowering informed decisions about clinical trials.
🗓 March 12, 3–4 PM EST
Register: als.net/als-town-hall/
Finding ALS trials shouldn’t be overwhelming.
The updated ALS Trial Navigator now features:
✔ Simplified experience
✔ Provider Quick Start
✔ NEALS-affiliated filter
Learn more:
als.net/news/the-als...
Today is National Caregivers Day.
To the extraordinary caregivers in the ALS community, thank you. Your strength and resilience fuel our urgency and push our research forward.
We see you. We honor you.
Champion Insights is open. The enrollment portal is live at championinsights.org.
At-home ALS research for high-risk/high-performance populations (endurance athletes, military, and first responders).
If you know someone who is eligible, please share.
#ALS #endALS
We’re excited to share that NEALS is partnering with ALS TDI on the ALS Trial Navigator.
People searching for clinical trials through NEALS can now use the ALS Trial Navigator on the ALS TDI website.
More updates coming in February!
Science can be powerful—and breathtaking. Congrats to Swetha Gurumurthy, Associate Scientist II, named runner-up in the Royal Society Publishing Photography Competition for her image of iPSC-derived motor neurons studying ALS.
Read more here: als.net/news/als-tdi...
🏀 Game on for a cause! This February, Hoops 4 ALS is bringing the heat with 4 Games you won’t want to miss.
Tune in or join us in person to cheer on the teams and help support ALS research. Let’s make every point count!
We’re excited to share that NEALS is partnering with ALS TDI on the ALS Trial Navigator.
People searching for clinical trials through NEALS can now use the ALS Trial Navigator on the ALS TDI website.
More updates coming in February!
You rode. You ran. You danced. You sold. You played. You hosted. You even raised a glass!
And together, events hosted by YOU raised $3.5 million for ALS research at ALS TDI in 2025.
We are endlessly grateful—and can’t wait to see where 2026 takes us. 💜
Beat the cold in style ❄️
Our new 'END ALS' winter beanies are here! Be sure to grab one while they last and help fuel ALS research.
Get yours today: alstdi.88blue.com
What started as a family love of running became a mission to #EndALS.
Connor McCullum ran the 2025 NYC Marathon for his dad after an ALS diagnosis—raising nearly $17K for research along the way.
Read the full story: als.net/news/connor-...
As we enter a new year, it’s time to take stock—not celebrate. Progress in ALS research happens quietly, over time, because people invest before certainty. In 2026, ALS TDI is focused on growth, acceleration, and urgency with rigor. Read more → als.net/news/on-prog...
AP-101 just advanced toward Phase 3 trials—and ALS TDI helped make it possible.
Years ago, donor support funded the unglamorous preclinical work behind this moment.
That’s the power of flexible research funding.
Read more: www.als.net/news/a-story...
What does it mean to be a nonprofit biotech?
At ALS TDI, it means inventing and advancing new medicines in our own lab—accountable only to the ALS community. Every dollar goes back into urgent, open ALS research. Your support fuels the science.
Donate: als.net/endals2025/?...
Happy holidays from all of us at ALS TDI. We’re deeply grateful for our community of supporters, scientists, and advocates who make our work possible. Wishing you a season filled with comfort, connection, and time with those you love.
LIMITED BIBS LEFT! Run for ALS research in:
🇫🇷 Hoka Semi de Paris
🇫🇷 Schneider Electric Marathon de Paris
🇦🇺 TCS Sydney Marathon
Apply NOW to join Team ALS TDI and make every mile count! als.net/news/2026-ma...
Emily is feeling inspired after an energizing four days at the 2025 Alliance Meeting & Allied Professionals Forum in San Diego, CA!
ARC’s in-home blood collection program is powering ALS discoveries — from genomics to biomarker research to global data sharing. 🧬
See how each blood draw accelerates progress at ALS TDI and beyond. Read the full blog: als.net/news/how-blo...
Every discovery brings us one step closer to treatments, and ultimately, an end to ALS. Our team is dedicated to understanding what causes ALS, so no one faces this disease without answers.
Team ALS TDI applications are OPEN for two new 2026 race opportunities! 🏃♂️💙
🇺🇸 United Airlines NYC Half — Mar 15, 2026
Apply: fundraise.als.net/marathon/nyc...
🇦🇺 TCS Sydney Marathon — Aug 30, 2026
Apply: sm26.grassrootz.com/the-als-ther...
🔔 Deadline: Dec 5, 2025
