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Posts by Pablo F. Céspedes

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Thrombospondin Encapsulated Dense Particles accelerate wound healing and downregulate fibrotic phenotypes Extracellular particles (EP) released by cells are heterogenous, with extracellular vesicles (EV) believed to be the major component. To investigate different EV subpopulations, we conducted a panel s...

A fascinating advance in extracellular biology — Claire’s new pre-print unveils Thrombospondin Encapsulated Dense Particles (ThrEDs), a new class of non-vesicular extracellular particles with potent wound-healing & anti-fibrotic activity.
📄 www.biorxiv.org/content/10.1...

#ExtracellularParticles

6 months ago 0 0 0 0
Statement on Supreme Court Ruling in American Public Health Association v. NIH - ASCB The American Society for Microbiology (ASM), the American Society for Biochemistry and Molecular Biology (ASBMB), the American Society for Cell Biology (ASCB) and the Federation of American Societies ...

ASM, ASBMB, ASCB & FASEB are deeply disappointed in the Supreme Court ruling allowing cancellation of $800M in NIH grants, threatening labs, jobs, and early-career scientists. Stable funding is vital for U.S. science.

Read more: www.ascb.org/society-news...

8 months ago 132 63 5 5
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Opinion | The Science I Would Be Doing if I Weren’t in ICE Detention

🧪 The personal testimony of a scientist at Harvard Med School now incarcerated by ICE in Louisiana:

“I haven’t been in my lab or worked with my microscope since February, when I was detained by ICE as I was returning to Boston from a vacation in France”

Gift link:

www.nytimes.com/2025/05/13/o...

11 months ago 141 63 3 6
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Now you see me: machine learning model makes spectra clearer Researchers have developed a machine learning model that helps interpret optical spectroscopy data.

Researchers at Rice University have developed a new machine learning model that makes optical spectroscopy data easier and quicker to interpret >>> www.biotechniques.com/computationa... 🧪

11 months ago 3 2 0 0

24 h of crowd power ➡️ live table of every placebo-controlled vaccine RCT

- 27 trials logged so far (>2 M participants)
- Control-type tag = saline vs active comparator

Contribute / explore 👇
bit.ly/3EuYzqI

cc @statnews.com @kffhealthnews.org

11 months ago 23 11 2 2

105 controlled vaccine trials.
110 yrs. 1.8 M participants.
All in one live, crowd-sourced sheet.

Built by contributors worldwide to counter the myth that vaccines weren’t tested with controls.

Quiet work still breaks through the noise.
www.bradspellberg.com/vaccine-rcts
@bradspellberg.bsky.social

11 months ago 194 101 6 5
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The plots of disaster movies that portray the end of civilization often begin with high-level Government Officials ignoring the warnings of Scientists.

One of several lesson learned from the 2.5 hour @Netflix Documentary — Don’t Look Up (2021).

11 months ago 14409 2274 460 123

Trumpty-Dumpty is defunding PBS. What he calls "bias" some of us call "facts Trumpty-Dumpty doesn't like."

11 months ago 41404 7547 1469 328
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Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".

11 months ago 45374 12438 1039 674