The deadline to submit an abstract to the "Virus & Brain" workshop (2-3 June 2026 - Montpellier, France) is approaching (April 1st) : www.atoutcom.com/workshop-vir...
Don’t miss this unique chance to connect with the international community and highlight your work!
@inserm.fr @cnrs.fr
Posts by Jules Bouget
The Trojan Horse is real, and it’s microscopic! 🐴🦠
Our paper is out today in @cellcellpress.bsky.social!
We discovered that deltaviruses physically hide INSIDE helper viruses to sneak into new cells. And to prove it, we had to image them from every angle. 🧵👇
www.sciencedirect.com/science/arti...
Using post-mortem human brain explants with @jvirolb.bsky.social and @gaudinlab.bsky.social, we could instigate RDeV replication within neural cells and show that upon VSV infection, these dual particles could be formed!
Neurons in 🟢, vessels in🟣 DNA in 🟡 and deltavirus in 🔵.
The Réseau thématique Virus-Cerveau @inserm.fr is pleased to announce that we will be organising our first 'Virus & Brain' International Workshop. @cnrs.fr
🧠Virus & Brain - 1st International Workshop
📅2-3 June 2026
📍Montpellier, France
The PhD work of Glaucia de Almeida, currently a postdoctoral researcher in the team working on viral neuroinfections using spatial proteomics, was recently highlighted in g1 Ribeirão e Franca.
g1.globo.com/sp/ribeirao-...
'When viral infections rewire neural circuits: towards cognitive virology'
by Jules Bouget, Emma Partiot & Raphael Gaudin
@jvirolb.bsky.social; @emmapartiot.bsky.social; @gaudinlab.bsky.social
www.cell.com/trends/neuro...
#Podcast 🎧 A L'UM la science #112 : "Vers la virologie cognitive ?"
🎙️▶️ smartlink.ausha.co/a-l-um-la-sc...
🗣️ Retrouvez toutes les émissions A L'UM la science : www.umontpellier.fr/articles/tag...
Viruses have evolved diverse mechanisms to cross the BBB, and crossing itself can cause damage. Notably, we question if brain invasion is required for neurovirulence, as peripheral-CNS signaling may allow non-neurotropic viruses to disrupt brain function. 6/6
Neuroimmunity regulates neuronal activity and is responsible for viral clearance. Virus-driven disruptions in signaling pathways that link antiviral immunity and synaptic homeostasis reveal the fine balance between infection and immune response. 5/6
By interacting with synaptic proteins and extensively reshaping the neuronal proteome, viruses remodel the molecular composition & function of synapses. We also underscore that synaptic organelles, crucial for local signaling, are primary targets of viral infections. 4/6
Many viruses alter neuronal activity and brain connectivity, disrupting the networks essential for complex cognitive functions. Viral infections impair synaptic transmission, leading to defecits in synaptic plasticity processes critical for memory formation and consolidation. 3/6
Clinical evidence suggests that severe and mild cognitive impairments can result from viral infections, sometimes lasting long after acute illness. Cognitive virology provides a framework integrating neurovirology, neuroimmunology, and neurobiology to examine viral impacts on human cognition. 2/6