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Posts by Daniel Promislow

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Research to help dogs live longer, healthier lives could unlock secrets for people to age better, too The Dog Aging Project is working to help dogs live longer, healthier lives. The research results may help humans age well, too.

The @dogagingproject.bsky.social team is so grateful to 60 Minutes and #andersoncooper for sharing our work on #dementia in #dogs. You can watch it on your local affiliate tonight, or later on YouTube.
www.cbsnews.com/news/longer-...

4 weeks ago 11 4 0 2
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In this new study, @dogagingproject.bsky.social identified overlapping metabolites linked to a subset of dogs and human mortality, supporting dogs as a compelling model for studying human aging. doi.org/10.1093/gero... @academic.oup.com

1 month ago 7 6 0 1

But it took just 2 years of Dog Aging Project data to discover these biomarkers, instead of the 10-20 years typically needed in human studies. Yet another reason why we love dogs!
@geronsociety.bsky.social

1 month ago 3 0 0 0
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Dogs and humans share biomarkers of mortality Abstract. There is growing interest in the use of molecular features as predictors of age, age-related disease risk and mortality. A major shortcoming of t

Happy to share our new paper from
the #dogagingproject. academic.oup.com/biomedgeront...
It turns out that metabolite predictors of mortality in dogs overlap significantly with those in humans.

@smacklab.bsky.social

1 month ago 20 9 2 0
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Morris Animal Foundation Opens Funding Call for Canine Health Research Proposals DENVER/March 5, 2026 – Morris Animal Foundation is now accepting pre-proposals for research to advance the health and welfare of dogs, including companion and working dogs.

Here's the latest call for proposals from the Morris Animal Foundation @morrisanimal.bsky.social. Lots of options, including a new opportunity for established investigators interested in #cancer, #aging and #longevity.
www.morrisanimalfoundation.org/article/morr...

1 month ago 3 2 0 0
Adapted from Axelsson et al. 2013 Fig 2c: Histogram showing the distribution of diploid amylase copy number in wolf (n=35, blue) and dog (n=136, red). Dogs carry more copies of the starch-digesting gene AMY2B than wolves. Additional copies make dogs better than wolves at digesting starchy foods like grains & vegetables.

Adapted from Axelsson et al. 2013 Fig 2c: Histogram showing the distribution of diploid amylase copy number in wolf (n=35, blue) and dog (n=136, red). Dogs carry more copies of the starch-digesting gene AMY2B than wolves. Additional copies make dogs better than wolves at digesting starchy foods like grains & vegetables.

Dogs evolved to eat your leftovers! Comparing dog & wolf genomes revealed dogs have up to 30 EXTRA copies of the amylase gene (AMY2B) that helps digest starch. This is a key genomic signature of living alongside humans & table scraps for thousands of years 🐕 www.nature.com/articles/nat... #2026MMM

1 month ago 467 147 10 26

Interested in metabolomics/systems biology and aging in Drosophila? We have a post-doc opening! And of course, there will be plenty of opportunities for side projects on the @dogagingproject.bsky.social. 🐶
promislowlab.org/wp-content/u...

4 months ago 9 10 0 0
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elmo from sesame street is sitting on a ledge with the words `` im so embarrassed '' . ALT: elmo from sesame street is sitting on a ledge with the words `` im so embarrassed '' .

Many years ago, I accidentally published a paper where I said “it is worth nothing” instead of “it is worth noting”. Only me to blame…

4 months ago 4 0 2 0
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I'm looking forward to speaking on CBC's The Current this morning all about dogs and aging! 🐕 🇨🇦@dogagingproject.bsky.social

4 months ago 5 0 0 0
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Early‐Life Climbing Stratifies the Metabolome and Mortality Risk in Genetically Identical Flies Isogenic Drosophila melanogaster vary greatly in longevity. Fractionation of an isogenic cohort based on climbing behavior early in life stratifies variation in the metabolome, longevity and mortalit...

I'm very happy to see this paper now out. We used early-life climbing ability to separate genetically identical short-lived and long-lived sub-cohorts of fruit flies, and to identify metabolites and metabolite modules that predict longevity.
onlinelibrary.wiley.com/doi/10.1111/...

4 months ago 5 2 0 0

Reposting our postdoc ad with the corrected link...

We have a new postdoc position available in the Promislow lab at the HNRCA at #Tufts in #Boston, to work on the #systemsbiology of #aging in #Drosophila. Come join us! For info on the position and to apply, see promislowlab.org/wp-content/u...

4 months ago 2 2 0 0

Apologies for the broken link to the ad. Here's the correct link: promislowlab.org/wp-content/u...

4 months ago 0 0 0 0

Reposting our postdoc ad to fix a broken link:

We have a new postdoc position available in the Promislow lab at the HNRCA at #Tufts in #Boston, to work on the #systemsbiology of #aging in #Drosophila. Come join us! For info on the position and to apply, see promislowlab.org/wp-content/u...

4 months ago 1 4 0 0

We have a new postdoc position available in the Promislow lab at the HNRCA at #Tufts in #Boston, to work on the #systemsbiology of #aging in #Drosophila. Come join us! For info on the position and to apply, see promislowlab.org/wp-content/u...

4 months ago 11 16 1 0

I think people adjacent to science (but who now find themselves deciding the fate of US science somehow) undervalue humility, valuing braggadocios hubris instead.
Yes it’s true that some scientific discoveries are complete paradigm changers, and we celebrate these. 1/

6 months ago 148 46 2 3
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Dog Aging Project Join the Dog Aging Project for a healthier future for dogs and humans.

The Dog Aging Project is alive and well, in part due to support from the 501(c)3 non-profit Dog Aging Institute. Thanks for your support!

6 months ago 1 0 0 0
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A decorative image of a white dog wearing a purple TRIAD Graduate bandana that reads, "Congrats Boudreaux, TRIAD Graduate." Find out if your dog is eligible for TRIAD: dogagingproject.org/triad

A decorative image of a white dog wearing a purple TRIAD Graduate bandana that reads, "Congrats Boudreaux, TRIAD Graduate." Find out if your dog is eligible for TRIAD: dogagingproject.org/triad

Exciting news from the TRIAD cohort! 🎉We’re celebrating another graduate from our clinical trial study! 🐶🎓

Want to help dogs live longer, healthier lives?
🐾 Discover if your doggo is eligible for TRIAD: dogagingproject.org/triad

#TRIAD #DogGrad #Dogs

6 months ago 4 2 0 0
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Promislow Lab Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University

www.promislowlab.org. ORCID 0000-0001-7088-4495

6 months ago 0 0 0 0
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Postdoctoral Scholar – Genomics, Aging, Somatic Mutation, Structural Variation, Evolution , Cancer – Integrative Biology University of California, Berkeley is hiring. Apply now!

The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested aprecruit.berkeley.edu/JPF05052

8 months ago 55 55 0 1
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Through our support of the @dogagingproject.bsky.social and similar studies of companion dogs, we strive to improve healthy aging by promoting research, providing funding, and educating the public.

🔍Learn more about us at dogaginginstitute.org

9 months ago 5 3 0 0

Having been one of the examiners on many an oral exam in evolutionary biology, I can tell you they are always action packed!

9 months ago 0 0 0 0
Members of the Promislow lab at the Anchorage conference center, with snowcapped mountains in the background.

Members of the Promislow lab at the Anchorage conference center, with snowcapped mountains in the background.

Our lab had a fantastic time at the @americanaging.bsky.social‬ #AGE2025 meeting in Anchorage. Well organized, terrific science, and glorious views of the mountains from the conference center!

11 months ago 19 1 0 0

The Dog Aging Institute is looking to hire an Executive Director to help grow this non-profit, whose mission is to support research on improving healthy #aging in #dogs. Interested? You can apply here: www.idealist.org/en/nonprofit...
@dogaginginst.bsky.social

11 months ago 1 3 0 0
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Inaugural editorial Inaugural editorial of Systems Aging.

Wishing the best of luck to Océane Cassan and her colleagues on the launch of "Systems Aging", a new journal at the intersection of #systemsbiology and #aging, from a new publisher. Based on this inaugural editorial, looks very promising! ephyrapublishing.com/articles/15ic.

11 months ago 2 0 0 0
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The Dog Days of Summer Shirt Campaign is live! These colorful, limited-edition designs are available for purchase, so snag yours before they're gone! ➡️ bonfire.com/dogdaysofsummer-shirtsale-2025

⚠️This is the only authorized shirt sale supporting the Dog Aging Project ‼️

#ShirtFundraiser #ShirtSale

11 months ago 2 2 0 1

Congratulations, Anne—wonderful news!!

11 months ago 1 0 0 0
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the word alert is in a purple circle ALT: the word alert is in a purple circle

ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n

11 months ago 364 447 17 59

For mortality rather than prevalence, you could use CDC data, such as the age/sex results summarized here www.cdc.gov/mmwr/volumes...

1 year ago 0 0 0 0
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Dog Aging Project Join the Dog Aging Project for a healthier future for dogs and humans.

And of course, if you'd like to have your dog join the other 50,000+ members of the Dog Aging Project Pack, just go to dogagingproject.org and click on the "Enroll Your Dog" button. We welcome dogs of all ages and sizes, mixed breed and pure breed, from every part of the US.

1 year ago 1 0 0 0
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Home - The Dog Aging Institute The Dog Aging Institute generates financial support, facilitates partnerships, and develops resources to advance innovative research into healthy aging in dogs.

There have been some reports about our funding challenges, but we are very much in operation and hard at work! And we have formed a non-profit, www.dogaginginstitute.org, so those interested can make a tax-deductible donation to support research on healthy aging in dogs. /fin

1 year ago 4 1 0 0