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Posts by Paul Masset

When it comes to sensory processing, cortex should not get all the credit... In olfaction, a key challenge is identifying odors regardless of concentration. Our new paper in @natneuro.nature.com shows how the olfactory bulb performs this crucial computation before signals even reach the cortex.

6 days ago 23 8 1 1

Delighted to share our discoveries about one of the brain's neurotransmitter systems:
www.biorxiv.org/content/10.6...

Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

1 week ago 239 113 6 16
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🌐 IVADO’s largest research mission to the US: a delegation of around 30 AI researchers strengthened collaborations with @princeton.edu, @columbiauniversity.bsky.social , @newyorkuniversity.bsky.social, and @cornelltech.bsky.social.
#Research #Innovation #Collaboration #R3AI

2 weeks ago 5 1 0 0
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Acetylcholine demixes heterogeneous dopamine signals for learning and moving Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...

Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...

3 weeks ago 155 68 2 3
Cosyne 2026 - Cosyne Tutorial: Comparative Analysis of Neural Population Codes
Cosyne 2026 - Cosyne Tutorial: Comparative Analysis of Neural Population Codes YouTube video by Cosyne Talks

Cosyne invited me to give a long tutorial (4 hours!) on methods to quantify differences high-d neural recordings across animals, brain regions, deep neural nets, etc.

The recording is up on youtube. I hope it inspires more research on this fundamental topic!

www.youtube.com/watch?v=n44x...

1 month ago 160 56 3 1

2-164 Population structure of reward-induced remapping in the hippocampal CA1
@chenjiang01.bsky.social with @ahalawa.bsky.social @mattyizhenghe.bsky.social @marisosa.bsky.social

1 month ago 7 2 0 0

1-188 The basal ganglia as a distributed reinforcement learning system computing general values
@zijingwu.bsky.social with Romane Charpentier Manoosh Samiei Doina Precup @itsnva7.bsky.social

1 month ago 6 0 1 1

The lab will be presenting two posters at #cosyne2026 #cosyne26 on dopamine-based distributed RL and hippocampal coding from a population-geometry perspective!
@zijingwu.bsky.social @chenjiang01.bsky.social

#compneurosky #neuroskyence

1 month ago 23 2 1 1
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New paper hot off the (pre-)press! We dig into the evolutionary origins of neural computations for behavioral control across mice, monkeys, and humans: www.biorxiv.org/content/10.6....

As our lab's first foray into comparative analysis of neural dynamics, I’m super excited about this work! 1/18

1 month ago 137 48 7 1
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Read our letter to Prime Minister Mark Carney – Canadian Association for Neuroscience Canadian Association for Neuroscience

Read CAN President Douglas Zochodne's letter to Prime Minister Mark Carney highlighting the importance of Neuroscience research and the CIHR Project Grant shortfalls.
can-acn.org/read-our-let...

1 month ago 17 11 0 0
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Join us at TENSS 2026 to open black boxes, explain how things/brains work and debate the impact (or lack or it) of various new technologies on understanding of the brain and on society. tenss.ro Apply by: March 15th!

1 month ago 18 17 0 0

We're thrilled to share that the Call for Workshops for this year's @rl-conference.bsky.social is now live!

As Workshop co-chair (alongside the wonderful Raksha Kumaraswamy and @claireve.bsky.social) we are looking forward to seeing the proposals for workshops that we receive.

LINK IN NEXT POST

2 months ago 11 5 1 2
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New paper alert! 🚨

We found that the brain's compass is remarkably stable at two scales

1️⃣ the system maintains its internal organization for weeks
2️⃣ It "remembers" its orientation for weeks, even after a single visit

This may be key to how the brain aligns its other maps.

Paper: rdcu.be/e3waP

2 months ago 199 69 5 7
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Our paper is out in @natneuro.nature.com!

www.nature.com/articles/s41...

We develop a geometric theory of how neural populations support generalization across many tasks.

@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social

1/14

2 months ago 278 101 7 1
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Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻

Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems.

See below for + details and retweet 🙏

2 months ago 75 56 3 5
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1/
📢 Come study cognitive science in Paris!
The Master’s program in Cognitive Science at @ENS_ULM, @psl_univ, and @EHESS_fr is now accepting applications for the next academic year.

🗓 Deadline: February 24, 2026
💻 Apply here: master-cognitive-science.ens.psl.eu/en/applicati...

3 months ago 19 19 1 3
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Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...

3 months ago 78 39 3 5

12 out of 10 stars. would recommend

3 months ago 12 4 2 0

I’m very happy to share the latest from my lab published in @Nature

Hippocampal neurons that initially encode reward shift their tuning over the course of days to precede or predict reward.

Full text here:
rdcu.be/eY5nh

3 months ago 105 32 2 2

With some trepidation, I'm putting this out into the world:
gershmanlab.com/textbook.html
It's a textbook called Computational Foundations of Cognitive Neuroscience, which I wrote for my class.

My hope is that this will be a living document, continuously improved as I get feedback.

3 months ago 590 238 16 10
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Emergent temporal abstractions in autoregressive models enable hierarchical reinforcement learning Large-scale autoregressive models pretrained on next-token prediction and finetuned with reinforcement learning (RL) have achieved unprecedented success on many problem domains. During RL, these model...

When we learn complex tasks, we chunk them into sub-tasks that our brains orchestrate into action sequences. How we do this is not entirely understood. This work explores how to learn and internally control temporally abstracted sub-tasks in RL/AI with sequence models. arxiv.org/abs/2512.20605

3 months ago 23 7 1 1
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🧠 New year, new preprint!

Why does motor learning involve multiple brain regions? We propose that the cortico-cerebellar system learns a "map" of actions where similar movements are nearby, while basal ganglia do RL in this simplified space.

www.biorxiv.org/content/10.6...

3 months ago 98 25 3 3
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How heterogeneity shapes dynamics and computation in the brain No two neurons are the same, yet models often treat neural populations as pools of identical and interchangeable elements. Here, Dahmen et al. highlight recent theoretical advances that reveal the imp...

At the Bernstein Conference 2024, Jeremie Lefebvre and I organized a workshop on the computational consequences of neural heterogeneity. Now, slightly more than a year later, we funneled the emerging discussions into a perspective piece: www.cell.com/neuron/fullt...

3 months ago 79 24 3 2

The RLC call for papers is out! A last minute bit of excitement before the holidays. Come join us at the conference every RL researcher complains about missing

3 months ago 19 2 0 0
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McGill’s Arts Building on campus, featuring its stone façade and green dome, with the McGill flag raised and autumn foliage surrounding the building.

McGill’s Arts Building on campus, featuring its stone façade and green dome, with the McGill flag raised and autumn foliage surrounding the building.

McGill is recruiting top-tier researchers working abroad through the federally funded Canada Impact+ Research Chairs program, addressing global and national challenges. The first round is due in early 2026.

Learn more and submit your candidacy: https://mcgill.ca/x/5Zh

4 months ago 23 20 0 3
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Canada-Impact-Plus - Research - Western University

If you're (1) into nhp neurophysiology and/or biological motor control, (2) a foreign big shot and (3) interested in moving here, please reach out -- this new program looks extremely attractive (min. $8M over 8y)! www.uwo.ca/research/can...

4 months ago 35 27 2 2
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Montreal AI & Neuroscience 2025 started this morning! 🧠X🤖

www.main2025.org

#MAIN2025
#NeuroAI
#Neuroscience
#AI

4 months ago 13 4 1 0
Administrative Opportunities

📣We have 2 open faculty positions for senior researchers in Neuroscience at Queen's University!

healthsci.queensu.ca/administrati...

1. a new Director for our Centre for Neuroscience Studies
2. a non-human primate NeuroAI researcher

Please share widely and reach out for questions!

4 months ago 48 65 1 4
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Environmental representations in mouse hippocampal CA1 reflect the predictive structure of navigation Predictive theories of cognitive mapping propose that these representations encode the predictive relationships among contents as experienced by the n…

Another new paper from the lab: Predictive theories like the SR imply that navigators who navigate differently should have cognitive maps which differ in predictable ways. Here we show that this holds in mouse hippocampal CA1.

www.sciencedirect.com/science/arti...

4 months ago 60 22 3 0
Image of robots struggling with a social dilemma.

Image of robots struggling with a social dilemma.

1/ Why does RL struggle with social dilemmas? How can we ensure that AI learns to cooperate rather than compete?

Introducing our new framework: MUPI (Embedded Universal Predictive Intelligence) which provides a theoretical basis for new cooperative solutions in RL.

Preprint🧵👇

(Paper link below.)

4 months ago 65 27 5 6