Learn what makes a great scientific graphic, from layout and color to clarity and accuracy. Perfect for authors preparing submissions to Allergy or any scientific publication.
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Our page explains the basics of creating effective Graphical Abstracts — clear, visual summaries that help readers grasp your findings in seconds.
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Zhao et al. demonstrate the role of keratinocyte TRPV3 as a critical driver of IL-33-mediated mast cell recruitment and inflammation in atopic dermatitis (AD). TRPV3 knockout mice exhibited significant reductions in perivascular mast cell density. In a mouse model of AD, inhibition of TRPV3, or the upstream protease-activated receptor 2 (PAR2), reduced IL-33 expression in the epidermis. The TRPV3-IL-33 axis was further demonstrated to regulate AD-associated substance P expression and neuro-mast cell interactions.
Open Access: Epidermal PAR2-TRPV3-IL-33 Signaling Promotes Mast Cell Recruitment and Sensory Nerve-Mast Cell Interactions in #AtopicDermatitis. First authors: Jiahui Zhao, LingXuan Zhou, and Chenyu Wang ; corresponding author: Miao Jing
👉 doi.org/10.1111/all.70284
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K.Yamamura, S.Garcet, J.Gonzalez, et al., “Sphingosine 1-Phosphate Receptor 1 and 5 Reciprocally Regulate IL-13 and IL-9 Production in Atopic Dermatitis,” Allergy (2026), doi.org/10.1111/all.70299
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Evaluation en vie Réelle de l'Allergo-Prescription en Pratique (ERAPP) is a large, prospective, real-world cohort of children and adults initiating named-patient product sublingual #immunotherapy (NPP-SLIT) in France. More than 80% of patients reported a clinically meaningful, expectation-anchored benefit (Patient Benefit Index ≥ 1) at 12–15 months. The Patient Benefit Index complements conventional patient-reported outcome measures by capturing what matters most to patients in routine allergy care.
Open Access: Patient-Perceived Benefits of Named-Patient Product Sublingual #Immunotherapy in Allergic Rhinitis and Asthma: Primary Results From the ERAPP Real-World Cohort Study. Corresponding author: Davide Caimmi
👉 doi.org/10.1111/all.70270
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M.Weiss-Tessbach, A. M.Dizdarevic, T.Bischof, et al., “Effect of Intramuscular Adrenaline on Histamine-Induced Hypotension: A Randomised Placebo-Controlled Pilot Trial,” Allergy 👉 doi.org/10.1111/all.70277
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In a population-based Prediction of Allergies in Taiwanese Children (PATCH) cohort aged 5-18 years, Wang et al. demonstrate that elevated fractional exhaled nitric oxide (FENO) levels during childhood independently predict incident allergic rhinitis over 6 years.
Open Access: Childhood Fractional Exhaled Nitric Oxide Predicts Incident Allergic #Rhinitis in Adolescence and Young Adulthood. First author: Chin-Hung Wang; corresponding author: Tsung-Chieh Yao
👉 doi.org/10.1111/all.70296
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T.Nomura, H.Tanida, T.Inoue, et al., “Family Size and #FoodAllergy in Early Childhood: The Japan Environment and Children's Study,” Allergy (2026), doi.org/10.1111/all....
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Bianchini, R., Escolar-Peña, A., Pick, V., Poli, A., et al. (2025), Molecular Signatures and Functional Pathways of Human Monocytes and Macrophages in Allergy: An EAACI AllergoOncology Scoping Review. doi.org/10.1111/all.16672
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In this study, Fukushima-Nomura et al. analyze the blood cytokine levels in atopic dermatitis patients to identify biomarkers that correlate with disease activity during dupilumab treatment, as measured by EASI scores. Among the cytokines analyzed, IL-22 and IL-18 retained measurable variability across various time points during treatment, demonstrating their potential as biomarkers for longitudinal monitoring.
Open Access: Interleukin-22 and Interleukin-18 as Potential Blood Biomarkers in Dupilumab-Treated #AtopicDermatitis. First author: Ayano Fukushima-Nomura; corresponding author: Hiroshi Kawasaki
Read the article here: doi.org/10.1111/all.70248
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Jerry Zhou from the Icahn School of Medicine at the Mount Sinai Medical Center, New York, USA, presents their research findings published in Allergy:
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This medical algorithm provides step-by-step clinical guidelines for the management of chronic #rhinosinusitis in the absence of nasal polyps upon endoscopic examination. Read other medical algorithms published in #Allergy here: journalallergy.com/Medical-Algorithms
Medical Algorithms: Management of Chronic #Rhinosinusitis Without Nasal Polyps. Heng Wang, Qingtai Yang, Micheal Soyka, Joaquim Mullol, De-Yun Wang, Zheng Liu
Read the article here: doi.org/10.1111/all.70271
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This study included 28 amoxicillin-allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free #amoxicillin or G4/G5-AXO dendrimers with successfully activated mast cells. Free amoxicillin and G4/G5-AXO dendrimers identified partially distinct patient subsets, increasing overall sensitivity when combined with optimal specificity.
Open Access: Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin. First author: Jose A. Céspedes; corresponding author: María José Torres
👉 doi.org/10.1111/all.70267
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Chiara Vasco from the Instituto Nazionale di Genetica Molecolare, Milan, Italy, presents their research findings published in Allergy:
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Early enhanced management of atopic dermatitis is associated with a lower 3-year prevalence of hen's egg and any #foodallergy. The difference is mainly attributable to a reduced history of raw egg allergy, consistent with earlier tolerance acquisition. Sustained atopic dermatitis control, growth, quality of life, and respiratory allergic outcomes are similar between intervention groups.
Three‐Year Follow‐Up of the PACI Randomized Controlled Trial (PACI‐ON): Effects of Early Intervention for #AtopicDermatitis on Atopic March. Corresponding authors: Kiwako Yamamoto-Hanada, Hajime Hosoi and Yukihiro Ohya
👉 doi.org/10.1111/all.70262
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Dr. Kamphuis was honored for his presentation: “Dietary fermentable carbohydrates promote mucosal mast cell-dependent type 2 immune responses and intestinal pain” His research sheds light on how diet-derived fermentable carbohydrates activate mucosal mast cells and promote type 2 immune responses — advancing our understanding of intestinal pain and immune dysregulation. Warm congratulations from the Allergy team!
🎉 Best Presentation Award – WIRM 20th Anniversary
Allergy is proud to sponsor the Best Presentation Award at the 20th edition of WIRM, and we are pleased to congratulate: Jasper Kamphuis, PhD Researcher (CRCN) at the French National Centre for Scientific Research (CNRS.
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Yale Liu from The Second Affiliated Hospital of Xi'an Jiaotong University presents their research findings published in Allergy:
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Open access: A One-Strength Dose Escalation Regimen for Birch Pollen SCIT Is Safe and Tolerable in Children, Adolescents, and Adult. Corresponding author: Marek Jutel
👉 doi.org/10.1111/all.70265
Read more articles 👉 journalallergy.com/Allergen-Specific-Immunotherapy
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Lee et al. analyse data from South Korean databases of individuals aged 50 or older and demonstrate that live zoster vaccination reduces the risk of #atopicdermatitis and #allergicrhinitis and that it persists for up to 6 years.
Live Zoster Vaccination and Reduced Risk of Atopic Dermatitis and Allergic Rhinitis. Kyeongmin Lee, Tae Hyeon Kim, Sooji Lee, Hayeon Lee, Dong Keon Yon
👉 doi.org/10.1111/all.70272
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Visit our website journalallergy.com for news from our EAACI Junior Members 👉 bit.ly/3SEgiwX
Read more on the latest JMA news and activities here 👉 journalallergy.com/JMA-Archive
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Henriette Farkas from Semmelweis University, Budapest, Hungary, presents their research findings published in Allergy:
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Melanie A. Ruffner, MD, PhD, studied biomedical engineering at Johns Hopkins and earned her MD and PhD in bioengineering from the University of Pittsburgh. She completed pediatric residency and Allergy and Immunology fellowship at Children's Hospital of Philadelphia, where she is now a practicing allergist–immunologist. She is an Assistant Professor of Pediatrics in the Division of Allergy and Immunology at the University of Pennsylvania's Perelman School of Medicine. Dr. Ruffner’s research focuses on pediatric food allergy, especially non–IgE-mediated diseases like eosinophilic esophagitis and FPIES. Her work is supported by the NIH and investigates epithelial barrier function, immune signaling, and mucosal responses to improve diagnosis and develop targeted treatments for affected children. She has authored numerous peer-reviewed publications on pediatric food allergy, eosinophilic gastrointestinal disorders, and mucosal immune mechanisms.
We welcome Dr. Melanie A. Ruffner as a new member of the Editorial Board of #Allergy.
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IL-10 producing CCR6+Th-cells are central memory T-cells that express ROR-γt and differentiate to Tr1 cells and Th17-cells via an autocrine loop of STAT3-activating cytokines (preTh17). STAT3-deficient autosomal dominant hyper-IgE syndrome (AD-HIES) patients lack Th17- and Tfh17-cells but retain preTh17- and Th1/17-cells. preTh17-cells in AD-HIES patients are activated by opportunistic pathogens to produce IL-10 and support IgE production.
Free access: Autosomal Dominant Hyper-IgE Syndrome Patients Retain IL10-Producing preTh17-Cells That Are Activated by Opportunistic Pathogens and Support IgE Production. Corresponding authors: Giorgia Moschetti, Chiara Vasco, and Jens Geginat. 👉 doi.org/10.1111/all.70266
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David A. Hill, MD, PhD, FAAP, FAAAAI Dr. David Hill is an Assistant Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania (Penn) and a Pediatric Allergist at the Children’s Hospital of Philadelphia (CHOP). He earned his Bachelor of Science from Carnegie Mellon University and his MD and PhD from Penn. Dr. Hill completed residency training in pediatrics and a clinical fellowship in allergy and immunology at CHOP. A nationally recognized expert in pediatric food allergy, Dr. Hill is an NIH R01-funded physician-scientist whose research has advanced the diagnosis and care of children with allergic and immune-mediated diseases. His lab studies the intersection of diet, the microbiome, and immune function. He has authored more than 100 peer-reviewed publications, including in Nature Medicine, Science Translational Medicine, and Pediatrics. His research has garnered national and international attention and has been featured in major media outlets including The New York Times, The Los Angeles Times, and on SNL’s Weekend Update. Dr. Hill serves on multiple national committees within pediatric and allergy organizations and is a member of the Editorial Board of Allergy and The Journal of Allergy and Clinical Immunology. He is deeply committed to mentorship and career development and has directly trained more than two dozen early-stage investigators. His honors include the American Society for Clinical Investigation (ASCI) Young Physician-Scientist Award, the Hartwell Foundation Individual Biomedical Research Award, and the AAAAI Faculty Development Award. He lives in Philadelphia with his wife and two children.
We welcome Dr. David Hill as a new member of the Editorial Board of #Allergy
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journalallergy.com/Who-are-We
Integrated bioinformatics and experiments identified shared key regulators of epithelial barrier dysfunction in #asthma, atopic #dermatitis, and ulcerative colitis. Upregulated CDC7, PXDN, TCN1, TIMP1 correlated with downregulated tight junctions; targeting CDC7 or TCN1 restored barrier integrity in airway, skin, and intestinal cells. Findings highlight CDC7 and TCN1 as promising therapeutic targets for diverse barrier dysfunction diseases.
Identification of Key Genes Associated With Epithelial Barrier Dysfunction by Comprehensive Analysis and Experimental Validation. Corresponding authors: Zhaowei Yang, Yingjun Chen, Jing Li 👉 doi.org/10.1111/all.70275
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Read more articles 👉 journalallergy.com/barrier-and-microbiota
Exhaled decane and nonadecane discriminate allergic rhinitis and local allergic rhinitis (AR + LAR) from non-allergic rhinitis and healthy controls (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb at baseline.
Open Access: Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic #Rhinitis. First author: Rosa Alba Sola Martínez; corresponding author: Teresa De Diego Puente 👉 doi.org/10.1111/all.70273
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journalallergy.com/Rhinitis-Sinusitis-Upper-Airways
This is a biographical article on Prof. Dr. Lawrence (Larry) Schwartz’s life and scientific achievements. His work laid the foundation for our current understanding of human mast cells and the diagnosis and management of associated diseases, including anaphylaxis and systemic mastocytosis.
Open Access: Legends of Allergy—Lawrence B. Schwartz
Gunnar P. Nilsson.
Read the article here: doi.org/10.1111/all.70290
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Read more biographical articles published in #Allergy here: journalallergy.com/Legends-of-Allergy-and-Immunology
The March issue is online! Check out the table of contents of the month. #Allergy_journal
onlinelibrary.wiley.com/toc/13989995/2026/81/3
In atopic dermatitis patients, this study compares the 2-year drug survival of biologics dupilumab and tralokinumab, and JAK inhibitors abrocitinib, baricitinib, and upadacitinib.
Open Access: Drug Survival in #AtopicDermatitis: Comparison of Biologics and JAK Inhibitors in the BioDay Registry. Corresponding author: Lian F. van der Gang
👉 doi.org/10.1111/all.70187
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Read more articles 👉 journalallergy.com/Atopic_Dermatitis_Urticaria_and_Skin_Disease
The cover of this issue illustrates this critical interface by depicting the developing microbiome of a child. The artwork highlights the early "window of opportunity" in childhood, during which the development of a diverse microbiome and the maturation of the protective epithelial barriers shape long-term immunological health. Advancing our understanding of these processes is essential for developing novel preventive and therapeutic interventions. © M Oeggerli (Micronaut) 2022, supported by UHB (Pathology) and Bio-EM Lab, Biozentrum, University Basel. journalallergy.com
📢New Issue! #Environment, #Microbiome and #EpithelialBarriers
According to the Epithelial Barrier Theory, disruption of tight junctions by environmental toxins, such as detergents, pollutants, and microplastics, drives the disease pathogenesis of many chronic inflammatory conditions
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Stay up-to-date with the latest research in allergy, asthma, and immunology through our Graphical Abstracts (GA) Gallery—updated monthly with over 800 GA! ✨ Highlights: • Visual summaries of cutting-edge research in your talks and lectures • Includes key article highlights • Freely downloadable PPT files for presentations and teaching • Perfect for researchers, educators, and clinicians
📊 Explore the Allergy Graphical Abstracts Gallery!
🔗 Visit the GA Gallery and download the files: journalallergy.com/GA-Archive
#AllergyResearch #Immunology #AsthmaResearch #GraphicalAbstracts #MedicalResearch #Allergy_journal
