Efficacy and safety of PPAR agonists in primary biliary cholangitis: a systematic review and meta-analysis of Randomized Controlled Trials - BMC Gastroenterology Background and aims Primary biliary cholangitis (PBC) is a chronic, progressive autoimmune liver disease. Some patients with PBC do not adequately respond to Ursodeoxycholic acid (UDCA) as a first-lin...

Read a great meta-analysis on PPAR agonists in PBC: 17 RCTs, 1,219 pts. Combo with UDCA ↓ ALP (−131), GGT, and bilirubin. Promising option when UDCA alone isn’t enou

DOI: doi.org/10.1186/s128...
#Hepatology #PBC #Gastroenterology #AutoimmuneLiver #PPAR #MetaAnalysis #ResidentReads #MedBluesk