U01.03.018 Bacterial endotoxin Bacterial endotoxins are lipopolysaccharide (LPS) molecules found in the outer membrane of Gram-negative bacteria. The lipid A component is toxic and responsible for activating macrophages and the complement system, leading to fever, hypotension, disseminated intravascular coagulation (DIC), and septic shock.

Bacterial endotoxins from Gram-negative bacteria cause fever, inflammation, and septic shock via lipid A activation. #BacterialEndotoxin #LPS #GramNegative #Sepsis #SepticShock #LipidA #Microbiology #Immunology #Pathophysiology #USMLE #MedicalEducation