Primary role of the Tol-Pal complex in bacterial outer membrane lipid homeostasis Gram-negative bacteria are defined by an outer membrane (OM) that contributes to envelope integrity and barrier function. Building this bilayer require proper assembly of lipopolysaccharides, proteins...

In case you missed it after switching platforms, the brilliant @weeboont.bsky.social also recently established the primary role of the Tol-Pal complex in outer membrane lipid homeostasis, using an engineered TonB-TolA chimera! Pls RT! #SGBUG #SCELSE_SG #ChemNUS
www.biorxiv.org/content/10.1...

Really excited to be sharing our newest work on the bacterial Tol-Pal complex! The amazing Jiang YEOW solved cryo-EM structures of the TolQRA complex in 2 rotary states, aiding us to come up with a model for force transduction across the cell envelope! Pls RT! #SGBUG #SCELSE_SG #ChemNUS