Pro-longed (+1 wk) FGF9 treatment in Takasato #KidneyOrganoid
👉Delays ectopic #Chondrogenesis
👉⏫AQP2
👉Reduces mesenchymal compartment
👉Enhances vascularization

The performance when implanted?🧐

Vanessa LaPointe lab #NPJRegMed 2025
www.nature.com/articles/s41...

ScienceDirect.com | Science, health and medical journals, full text articles and books.

We’re thrilled to share our new collaborative study with the Kimber group @manchester.ac.uk #SingleCell transcriptomics identifies chondrocyte differentiation dynamics in vivo and in vitro 🧬🦴 authors.elsevier.com/sd/article/S...
#Chondrogenesis #HumanCellAtlas ‪@scicambridge.bsky.social ‬

In this work my team and co-workers demonstrated a purely mechanically regulated route for #StemCell #Chondrogenesis via engineering of the hydrogels #viscous nature. No #growthfactors needed. Conducted @uofglasgow.bsky.social @theglasgowcemi.bsky.social Funded @ukri.org