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Development of a Novel Liquid Chromatography Coupled to Multiple Reaction Monitoring (LC-MRM) Assay for the Quantification of Neurofilament Light Chain in Cerebrospinal Fluid and Comparison with Ultra-Sensitive Immunoassay: A Step toward Standardization #ClinChem academic.oup.com/clinchem/art...

🏅 Congratulations to UCLA Pathology's Dr. Allison Chambliss on being selected for the Association of American Medical Colleges (AAMC) 2025 Midcareer Faculty Leadership Development Seminar!

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💫 Our Clinical Chemistry Fellowship is now accepting applications! #pathology #path2path #PathX #Fellowship #ClinChem ⚗️🧪

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In Vitro Metabolic Profiling of 18 Semi-Synthetic Cannabinoids—Hexahydrocannabinol (HHC) and Its Analogs—with Identification in an Authentic Hexahydrocannabiphorol (HHCP) Urine Sample AbstractBackground. Hexahydrocannabinol (HHC) and its analogs are recent additions to semi-synthetic cannabinoids in the recreational drug market. Here, th

Recently out in #ClinChem & worth a read: Watanabe and colleagues, "In Vitro Metabolic Profiling of 18 Semi-Synthetic Cannabinoids—Hexahydrocannabinol (HHC) and Its Analogs—with Identification in an Authentic Hexahydrocannabiphorol (HHCP) Urine Sample"
academic.oup.com/clinchem/adv...

In Vitro Metabolic Profiling of 18 Semi-Synthetic Cannabinoids—Hexahydrocannabinol (HHC) and Its Analogs—with Identification in an Authentic Hexahydrocannabiphorol (HHCP) Urine Sample AbstractBackground. Hexahydrocannabinol (HHC) and its analogs are recent additions to semi-synthetic cannabinoids in the recreational drug market. Here, th

In Vitro Metabolic Profiling of 18 Semi-Synthetic Cannabinoids—Hexahydrocannabinol (HHC) and Its Analogs—with Identification in an Authentic Hexahydrocannabiphorol (HHCP) Urine Sample #ClinChem #MassSpec academic.oup.com/clinchem/art...

Instrument Multiplexing: Amplified Throughput for Measurement of Vitamin B1 in Whole Blood Using Parallel Liquid Chromatography Systems Interfaced to a Single Mass Spectrometer AbstractBackground. Thiamine diphosphate (TDP), the active form of vitamin B1, plays an essential role in energy metabolism. TDP is analyzed in the clinica

Instrument Multiplexing: Amplified Throughput for Measurement of Vitamin B1 in Whole Blood Using Parallel Liquid Chromatography Systems Interfaced to a Single Mass Spectrometer #ClinChem academic.oup.com/clinchem/adv...

Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes AbstractBackground. Methylglyoxal (MGO) is a potent glycating agent that contributes to the pathogenesis of diabetes. However, MGO is unstable in plasma wi

Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes #ClinChem #MassSpec academic.oup.com/clinchem/adv...

Measurement of Serum Free Vitamin D Concentrations: Importance, Challenges, and the Emerging Role of Mass Spectrometry AbstractBackground. Serum total 25-hydroxyvitamin D [25(OH)D] concentration is the most widely used clinical biomarker for vitamin D status. Under certain

Here is the latest review paper from my group:

Measurement of Serum Free Vitamin D Concentrations: Importance, Challenges, and the Emerging Role of Mass Spectrometry #ClinChem academic.oup.com/clinchem/adv...