Spatial transcriptomics uncovers hybrid, proinflammatory, and profibrotic cellular niches in pulmonary granuloma of patients with chronic sarcoidosis AbstractBackground. Sarcoidosis is a disease of unknown etiology, characterized by the formation of immune cell accumulations (granulomas) in the lung and

In diseases like Sarcoidosis Granulomas are ubiquitous and mysterious, and RIPE to be demystified by spatial omics analysis.
Kudos @jonas_schupp for this groundbreaking work. Read paper at academic.oup.com/ajrccm/artic...
#CureSarcoidosis

First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate | NEJM Prednisone is currently recommended as the first-line treatment for pulmonary sarcoidosis but is associated with many side effects. Methotrexate, which is recommended as a second-line treatment, ap...

Wow! The first Sarcoidosis RCT in NEJM this century came out just in time for #ATS2025 - Methotrexate is equal to Prednisone as 1st line. What a first great step. Let's hope many more will follow!!! 👏🏼 Drs Kahlmann, Wijsenbeek #PREDMETH team!!
#CureSarcoidosis
www.nejm.org/doi/full/10....