🔊 #D2RProjectSpotlight: D2R - Health Data Science (D2R-HeDS) platform 💡 Scientific Director: Guillaume Bourque (@McGillu) 🔗 Learn more: buff.ly/qDphDDy
#RNA #RNATherapy #RNAResearch

#D2RProjectSpotlight: End to end sequencing platform for RNA therapeutics quality control (EESPRNATQC) Scientific Director: Ioannis Ragoussis (@mcgillu)🔗 Learn more here: buff.ly/zhzGYc7

🔊 #D2RProjectSpotlight: Centre for Applied Nanomedicine (CAN)💡 Scientific Director: Janusz Rak (RI-MUHC)🧬 Centre for Applied Nanomedicine (CAN) is a place/platform where specialized instruments measure, observe, and characterize myriads of small objects known as nanoparticles 🔗 buff.ly/Hv3NYJV

#D2RProjectSpotlight: RNA therapies for the treatment of a rare neurological disease led by Jo Anne Stratton (@mcgillu) This project aims to understand how RNA-based therapies can be optimized to target Schwann cells, the major cell type affected in Neurofibromatosis type 2.🔗 buff.ly/QYf2Kfg

🔊 #D2RProjectSpotlight: RNA therapeutics to block USP15-driven neuroinflammation in the brain led by Philippe Gros (@mcgillu) this project aims to test the capacity of these USP15 modalities to block neuroinflammation in vivo following delivery to the brain. Learn more: buff.ly/P0QfkgL

🔊 #D2RProjectSpotlight: mRNA Therapy to Prevent Liver Disease Progression in Zellweger Spectrum Disorder led by Nancy Braverman (@McGillu) ZSD is a rare genetic disorder, most patients harbor mutations in PEX1 gene. This project aims to restore PEX1 function. Learn more: buff.ly/3Y93ZQY

🔊 #D2RProjectSpotlight: Aptamer-short hairpin RNA conjugation for gene therapy against HIV led by Anne Gatignol (Jewish General Hospital)🧬This research aims to support a more effective procedure in which a person's own cells are modified to make them resistant to HIV.🔗 buff.ly/WudYn1G

🔊 #D2RProjectSpotlight: Lipid Nanoparticles for Nasal mRNA Vaccines💡 Led by Larry Lands (RI-MUHC) 🧬 This project explores delivering RNA vaccines through a nose spray. This nasal method is not only more convenient but could offer better protection for the lungs. 🔗 Learn more: buff.ly/raSze21

🔊 #D2RProjectSpotlight: 3’UTR engineering for next-generation T cell mRNA therapeutics led by Thomas Duchaine (@mcgillu) This project aims to improve cancer immunotherapies by designing “smart” RNA switches that control how long therapeutic mRNAs stay active in immune cells. buff.ly/iyMZTzA

🔊 #D2RProjectSpotlight: Development of RNA therapeutics against USP15-dependent neuroinflammation led by Philippe Gros, PhD🧬This project aims to develop inhibitors of USP15 which can dampen neuroinflammation using an RNA therapeutics approach. 🔗 Learn more: buff.ly/o3CRrRl

🔊 #D2RProjectSpotlight: Targeting MET exon 14 skipping variant in the early metastatic dissemination in lung cancer 🧬 Led by Morag Park (@mcgillgci.bsky.social) this project aims a novel therapy using targeted molecules designed to block this mutation. 🔗 buff.ly/VfPel6h

#D2RProjectSpotlight: Injectable Hydrogel/mRNA-LNP Platform for In Vivo CAR-T Cell Engineering 🧬Led by Guojun Chen (@McGillu) this project aims to accelerate the development of next-generation immunotherapies buff.ly/Xa2wnaT

#D2RProjectSpotlight: Transient CAR-T Cell engineering🧬Led by Taha Azad (@USherbrooke) this project aims to produce safe & effective CAR-Ts, and help accelerate RNA-based cell therapy development buff.ly/Tsz4eBD

#D2RProjectSpotlight: Development of a new blood test to track treatment success and to detect melanoma returning early🧬Led by Ian Watson (@mcgillu) this project aims to improve care for melanoma patients. buff.ly/7cVwU65

#D2RProjectSpotlight

🧬 This project, co-funded by Médicament Québec, RNA Technologies and Therapeutics Inc., AReNA, NovoArc GmbH, and the Victor Phillip Dahdaleh Institute, aims to advance next-generation mRNA vaccines.

🔗 Learn more: buff.ly/NlIVF16
@mcgill-research.bsky.social

#D2RProjectSpotlight: Identifying pathogen targets for next-gen Mpox vaccines

🧬 Led by Jörg H. Fritz @mcgill.ca , this study aims to discover new targets for Mpox vaccines with ‪@dalhousieu.bsky.social‬ & University of Vienna

🔗 Learn more: buff.ly/OVYIXiI
#RNA #VaccineDevelopment

🔊 #D2RProjectSpotlight: Pre-clinical mouse models to study RNA vaccines for Poxvirus

🧬Led by Silvia Vidal at @mcgill.ca , this project uses mouse models to evaluate new RNA vaccine approaches for poxvirus infection

🔗 Learn more: buff.ly/TwTQFGG
#RNAResearch
‪@mcgillscience.bsky.social

🔊 #D2RProjectSpotlight: McGill Centre for Translational Research in Cancer

Scientific Director: Gerald Batist

MCTRC addresses an unmet need, bridging the gap between academic research and clinical practice.

🔗 Learn more: buff.ly/4275XSl

🔊 #D2RProjectSpotlight: @genomicsandpolicy.bsky.social

Scientific Director: Yann Joly

The Centre of Genomics and Policy at @mcgill.ca is an interdisciplinary research hub focused on law, medicine, bioethics, governance, and public policy in genomics and health.

🔗 Learn more: buff.ly/3DOzM07

🔊 #D2RProjectSpotlight: The McGill Research Center on Complex Traits

Scientific Director: Jörg Fritz

The Center combines genetic/genomic approaches with immunological studies to uncover mechanisms of pathogenesis in infectious and inflammatory diseases.

🔗 https://buff.ly/4gCEv3r

🔊 #D2RProjectSpotlight: McGill Centre for Viral Diseases

Scientific Director: Chen Liang

The Centre seeks solutions to life-threatening viral diseases through advancing research, enhancing visionary education, and adopting cutting-edge technology.

🔗https://buff.ly/3DZrSRm

📣 #D2RProjectSpotlight: @mcgillgci.bsky.social
Scientific Director: Morag Park

Supported by D2R’s Centre & Institutes Support program, GCI is advancing precision medicine, immunotherapy, predictive biomarkers & early detection to support D2R’s mission.

🔗https://buff.ly/427LcWY

🔊 #D2RProjectSpotlight: Internship program in biomanufacturing

Principal Investigator: Amine Kamen

Allows students to gain deeper knowledge and technological skills in bioprocessing and biomanufacturing in industry settings.

🔗 buff.ly/4j9B5qv

🔊 #D2RProjectSpotlight: This project, led by Jo Anne Stratton (@mcgill.ca) aims to optimize RNA therapies to reverse cytotoxicity in ALSP patients & provide a disease-modifying treatment.

🔗https://buff.ly/40bYGOC

@theneuro.bsky.social @ircm.bsky.social
@martinsauvageau.bsky.social

#RNA

🔊 #D2RProjectSpotlight: Therapeutic development of the CRISPR-Cas12a gene editing system

Principal Investigator: Masad Damha (McGill University)

This project involves nucleic acid chemistry and biology aimed at enhancing the drug-like properties of RNA therapeutics.

🔗https://buff.ly/40tQ8D9