A predictive model for life-threatening fluoropyrimidine toxicity based on DPYD sequencing in colorectal cancer - PubMed DPYD sequencing identified additional relevant variants and improved the sensitivity of DPYD testing. An online calculator (https://fluoropyrimidine-toxicity-predictor.gustaveroussy.fr/) is provided to estimate the individual probability of developing life-threatening toxicity, based on clinical cov …

Latest paper. Improving sensitivity for detecting fluoropyrimidine toxicity #pharmacogenetics #DPYDgenotype pubmed.ncbi.nlm.nih.gov/41386266/