U01.02.033 Immunodeficiencies B- & T- cell disorders  Explore the causes, classifications, and clinical features of primary and secondary immunodeficiencies focusing on B-cell and T-cell disorders. Learn how defects in humoral and cellular immunity lead to increased susceptibility to infections, autoimmune diseases, and malignancies.

Learn the key differences between B-cell and T-cell immunodeficiencies, their causes, and clinical features to master immunology for exams and practice. #Immunodeficiency #BCellDisorders #TCellDisorders #Immunology #MedicalEducation #USMLE #Pathology #SCID #DiGeorgeSyndrome #ClinicalImmunology

U01.02.032 Immunodeficiencies T-cell disorders Analyze the clinical scenario step-by-step. Identify the patient’s age, types of infections (viral, fungal), associated features (hypocalcemia, congenital heart defects, facial anomalies), and lab findings (low T-cell count, low PTH). Use these key clues to connect the presentation to a developmental defect involving the pharyngeal pouches and determine the most likely underlying genetic abnormality.

Master the fundamentals of T-cell immunodeficiencies — understand their pathophysiology, infections associated, and clinical relevance for diagnostic and therapeutic insight.
#TCellDisorders #Immunology #SCID #DiGeorgeSyndrome #USMLE

Human ectodermal organoids reveal the cellular origin of DiGeorge Syndrome
Apati, A., Barbosa Sabanero, K. et al.
Paper
Details
#DiGeorgeSyndrome #EctodermalOrganoids #GeneticResearch

Where's my 22q Deletion Syndrome family? Are we on Bluesky yet? #22q #22qdeletionsyndrome #digeorgesyndrome

FYI, I have #DigeorgeSyndrome anyone else? I'm the crazy with an excuse. IDK about the other ones who are though, better get some meds before RFK bans them.

#22q11.2 #DiGeorgeSyndrome #awareness #medicalmom