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Scientific figure showing experiments in fruit flies testing cell ablation with Ronidazole and Nitroreductase. Top panels: images of adult flies with normal eyes vs. reduced or absent eyes after treatment, quantified in a bar graph. Middle panels: fluorescent images of eye discs showing GFP-labeled cells and Dcp1 staining, with increased cell death after treatment. Bottom panels: brain images showing targeted ablation of insulin-producing cells and cortex glia, confirmed by loss of GFP and presence of Dcp1. Graphs show significant reduction in specific cell types with Ronidazole treatment.

Scientific figure showing experiments in fruit flies testing cell ablation with Ronidazole and Nitroreductase. Top panels: images of adult flies with normal eyes vs. reduced or absent eyes after treatment, quantified in a bar graph. Middle panels: fluorescent images of eye discs showing GFP-labeled cells and Dcp1 staining, with increased cell death after treatment. Bottom panels: brain images showing targeted ablation of insulin-producing cells and cortex glia, confirmed by loss of GFP and presence of Dcp1. Graphs show significant reduction in specific cell types with Ronidazole treatment.

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Spatiotemporal control of cell ablation using Ronidazole with Nitroreductase in Drosophila

by Gary Teeters, Christina Cucolo, Sagar Kasar, Melanie Worley, and Sarah Siegrist

tiom33.short.gy/DB520,31-40

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