Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR Abstract. Understanding mRNA regulation by microRNA (miR) relies on the structural understanding of the RNA-induced silencing complex (RISC). Here, we eluc

Can increasing the sensitivity of #NMRspectroscopy provide some insight into #microRNA and #Argonaute interaction?
The answer is a resounding Yes.
Find out more in our recent study where we used #DynamicNuclearPolarisation to study this complex
doi.org/10.1093/nar/...