Extrachromosomal DNA circles fuel pancreatic cancer’s aggression – BioNews Central New findings indicate that extrachromosomal DNA is a hidden factor contributing to the adaptability and treatment resistance of pancreatic cancer, which has a five-year survival rate of only 13% due to late detection. ...

New findings indicate that #ExtrachromosomalDNA is a hidden factor contributing to the adaptability and #TreatmentResistance of #PancreaticCancer, which has a five-year survival rate of only 13% due to #LateDetection.

🧬 New @nature.com study from the #UniversityOfVerona, @uofglasgow.bsky.social & @champalimaudf.bsky.social alimaudf.bsky.social uncovers how #extrachromosomalDNA (#ecDNA) helps pancreatic tumours resist therapy & survive.
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Coordinated inheritance of extrachromosomal DNAs in cancer cells - Nature Cooperative species of extrachromosomal DNAs are coordinately inherited through mitotic co-segregation.

Coordinated inheritance of extrachromosomal DNAs in cancer cells. #ExtrachromosomalDNA #ecDNA #CancerCells @natureportfolio.bsky.social
www.nature.com/articles/s41...