📝 Online now - the Review "Molecular mechanisms of the mammalian fatty acid cycle" from Christian Gusenda and @m-grininger.bsky.social.

#FattyAcidBiosynthesis #FattyAcidSynthase #FAS #mFAS #AcylCarrierProtein #ACP

Read it here 👉 authors.elsevier.com/sd/article/S...

This study reveals that #FattyAcidSynthase inhibition via PPIs enhances poly (ADP-ribose) polymerase inhibitor (PARPi) efficacy in #TripleNegativeBreastCancer (TNBC), offering a strategy to combat PARPi resistance in #TNBC. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...

Fatty acid factory filmed at work Researchers have visualized the fatty acid synthase structure in unprecedented detail.

Teams led by Holger Stark & Ashwin Chari have visualized the #FattyAcidSynthase #FAS structure at a 1.9 angstrom resolution! They filmed the FAS at work for the first time and reconstructed a complete fatty acid biosynthesis cycle. @Leibniz_DSMZ_en https://www.mpinat.mpg.de/4550258/pr_2319