#VegetableRes
Excessive fertilizers and continuous cropping cause salt stress, reducing tomato yield by disrupting the cell cycle and promoting early flowering.
Details: maxapress.com/article/doi/10.48130/veg...
#Agriculture #TomatoYield #InnoConf24

Cooperation and innovation: An interview with Minister Ibrokhim Y. Abdurakhmonov and Professor Jinghua Cao #InnoConf24

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Construction and investigation of all-in-one microneedles complexed with functionalized polydiacetylene liposomes for improved in situ detection sensitivity Polydiacetylene (PDA) liposomes have been widely applied for detection due to their distinctive optical properties. However, the liquid phase in which…

Construction and investigation of all-in-one microneedles complexed with functionalized polydiacetylene liposomes for improved in situ detection sensitivity #InnoConf24
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Targeted protein editing technique in living mammalian cells by peptide-fused PNGase Various precise gene editing techniques at the DNA/RNA level, driven by clustered regularly interspaced short palindrome repeats (CRISPR)/CRISPR-assoc…

Development of targeted protein editing technique in living mammalian cells by peptide-fused PNGase #InnoConf24
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Cooperation and innovation: An interview with Minister Ibrokhim Y. Abdurakhmonov and Professor Jinghua Cao #InnoConf24
@yanqun393

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HiTIP-seq profiles epigenomic reprogramming of patient-derived diffuse midline glioma stem cells to epigenetic therapy Diffuse midline glioma (DMG), H3K27-altered, is lethal pediatric-type, high-grade, localized to the midline region of the central nervous system. Effe…

HiTIP-seq profiles epigenomic reprogramming of patient-derived diffuse midline glioma stem cells to epigenetic therapy #InnoConf24
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Single-cell omics in tracing cellular heterogeneity of drug-induced liver injury: Technological landscape and prospective application Drug-induced liver injury (DILI) remains a serious problem in clinics for both diagnoses and treatment decisions. It is a result of accumulated drugs …

Single-cell omics in tracing cellular heterogeneity of drug-induced liver injury: Technological landscape and prospective application #InnoConf24
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Discoidin domain receptor 1 as a potent therapeutic target in solid tumors Despite significant discoveries in basic cancer research and improvements in treatment options and clinical outcomes, cancer remains a major public he…

Discoidin domain receptor 1 as a potent therapeutic target in solid tumors Author links open overlay panel #InnoConf24
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Dysregulated STAT1 gain-of-function: Pathogen-free autoimmunity and fungal infection Inborn errors of the signal transducer and activator of transcription 1 (STAT1) result in four types of immunodeficiency disease with varying degrees …

Dysregulated STAT1 gain-of-function: Pathogen-free autoimmunity and fungal infection #InnoConf24
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Regulatory functions and mechanisms of human microbiota in infectious diseases The human microbiota, a diverse community of microorganisms living on or within their hosts, play an irreplaceable role in maintaining human health. D…

Regulatory functions and mechanisms of human microbiota in infectious diseases #InnoConf24
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Kha-Ti Lim: Mother of Ten Thousand Infants #InnoConf24
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TLR5 expression marks brain boarder associated macrophages and protects neonatal mice from bacterial meningitis #InnoConf24
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A cholangiocyte organoid system for Cryptosporidium parvum cultivation and transcriptomic studies of biliary cryptosporidiosis Biliary cryptosporidiosis caused by Cryptosporidium is life-threatening in immunocompromised individuals, particularly those with acquired immune defi…

A cholangiocyte organoid system for Cryptosporidium parvum cultivation and transcriptomic studies of biliary cryptosporidiosis #InnoConf24
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Cancer research revolutionized: Unveiling the power of organoids and their therapeutic potential in oncology Organoids are in vitro microstructures similar to the source tissue formed by the self-organizing construction of stem cells from various sources. It …

Cancer research revolutionized: Unveiling the power of organoids and their therapeutic potential in oncology #InnoConf24
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Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1 Antibodies targeting non-structural protein 1 (NS1) confer protection against Zika virus (ZIKV). Although monoclonal antibodies (MAbs) 3G2 and 4B8 are…

Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1 #InnoConf24
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Nasal mucosal secretory immunoglobulin A but not serum antibodies is resistant to Omicron evasion #InnoConf24
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BCMA-CD19 bispecific CAR-T therapy in refractory chronic inflammatory demyelinating polyneuropathy #InnoConf24 @ MingShi @GuiyunCui @JunnianZheng
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Ism1 deficiency in mice exacerbates bleomycin-induced pulmonary fibrosis with enhanced cellular senescence and delayed fibrosis resolution Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease with high morbidity and mortality but unclear etiology and in…

Ism1 deficiency in mice exacerbates bleomycin-induced pulmonary fibrosis with enhanced cellular senescence and delayed fibrosis resolution #InnoConf24 @MahalakshmiShanmugasundaram @RuowenGe
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Surpassing the natural limits of serological diagnostic tests #InnoConf24 @DWilliamProvanceJr
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Boosting CAR-T cell therapy with CRISPR technology Chimeric antigen receptor (CAR)-T cell therapy has made remarkable breakthroughs in treating cancers, especially hematologic malignancies, yet its bro…

Boosting CAR-T cell therapy with CRISPR technology #InnoConf24
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Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study During the continuing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the Omicron variant of concern emerged in the second …

Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K #InnoConf24
@JanaShenLab
@RolfHilgenfeld
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Understanding carbapenem-resistant hypervirulent Klebsiella pneumoniae: Key virulence factors and evolutionary convergence The emergence of hypervirulence (hv) and carbapenem resistance (CR) as distinct evolutionary directions for Klebsiella pneumoniae presents a significa…

Understanding carbapenem-resistant hypervirulent Klebsiella pneumoniae: Key virulence factors and evolutionary convergence #InnoConf24
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Population genomics of Central Asian peoples unveil ancient Trans-Eurasian genetic admixture and cultural exchanges #InnoConf24
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Histoplasmosis misdiagnosed as malignancies in immunocompetent and immunocompromised patients: A global perspective on clinical presentation, radiological and pathological findings #InnoConf24
@Basseyekeng5

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Recent advances in surgical management strategies for hepatocellular carcinoma Hepatocellular carcinoma (HCC) is a significant global health challenge, requiring innovative methods to improve patient survival. Due to different di…

Recent advances in surgical management strategies for hepatocellular carcinoma #InnoConf24
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Discovering broader antiviral strategies: Role of interferon-induced transmembrane proteins in virus infection #InnoConf24
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#ForestryRes

🌸Our study in Fraxinus mandshurica peels back the layers on stigma development. ROS and flavonoids take center stage in pollination.

#ros #pollen #InnoConf24

Details: maxapress.com/article/doi/...

CDK4/6 inhibition: What’s happening beyond CDK4/6 inhibition may also matter

Check out our editorial on the diverse effects of CDK4/6 inhibitors beyond cell cycle arrest, highlighting their potential in immune modulation and cancer therapy! @theinnovation.bsky.social

www.the-innovation.org/article/doi/...

#InnoConf24 #Immunotherapy
#science #medicine