📣 Who is behind #Kingella kingae, #Elizabethkingia
meningoseptica, and several other bacteria? Anne-Marie Dolan et al describe the legacy of Elizabeth O. King, #CDC microbiologist & World War II army officer, for our #Personbehindthename series.
#IDSky #clinmicro
www.cmi-comms.org/article/S295...
#kingella isolates are usually susceptible to penicllins, cephalosporins, FQ, AG, tmp-smx, macrolides although a plasmid encoded B lactamase has been found in few strains
#kingella diagnosis is made by recovering organisms in cultures from normally sterile body fluid (blood, joint aspirate), difficulty in isolation can lead to incorrect dx of culture neg bone or joint infection. PCR are more sensitive than culture for joint fluid
In the absence of endocarditis, slow clinical improvement of septic arthritis #Kingella kingae should raise suspicion of a deep-seated infections as endovascular source, especially for patients with risk factors for atherosclerosis, such as a history of smoking #iddailypearl
In this case: #kingella septic arthritis seemed to have been a complication of infected vascular lesion in femoral artery, caused either by seeding after bacteremia or after septic emboli to L leg, including knee & skin of sole of foot
#Kingella kingae adult IE, native or prosthetic valves. Clear oral source for the invasive infection in some cases. After transient bacteremia, the pathogen seeds heart valves that have damaged endothelium.
#Kingella kingae gram-negative coccobacillus, normal flora of upper respiratory tract. Causative agent of osteoartricular infections in kids<4 years. Rarely HACEK IE in adults
R.f poor oral hygiene, pharyngitis, & mucosal ulcerations
