Louse borne relapsing fever #LBRF #borrelia #recurrentis
ddx
-falciparum malaria
-yellow fever
-other Viral Hemorrhagic F as Rift Valley Fever
-viral hepatitis
-rickettsial infection
-Trench fever (Bartonella quintana
-typhoid
#LBRF can be treated with a single dose of intramuscular penicillin or a single dose of a tetracycline. Patients should be observed for a Jarisch-Herxheimer reaction after treatment
#LBRF Severe dz shock, myocarditis ARDS, cerebral or gastrointestinal bleeding, ruptured spleen, hepatic failure, Jarisch–Herxheimer reactions & opportunistic typhoid or other bacterial infections. Pregnant women are at high risk of aborting and perinatal mortality is high.
louse borne relapsing F #LBRF by inoculation of body louse feces by scratching. Relapse F due to antigenic variation of borrelial outer-membrane lipoprotein. ⬆️F, rigors, headache start abruptly 2-18d postexposure. Petechial rash, epistaxis, jaundice, hepatosplenomegaly common.
#LBRF ddx
falciparum malaria
yellow fever
other VHF as Rift Valley Fever
viral hepatitis
rickettsial infection LBRF
Trench fever (Bartonella quintana
typhoid
#LBRF can be treated with a single dose of intramuscular penicillin or a single dose of a tetracycline. Patients should be observed for a Jarisch-Herxheimer reaction after treatment
#LBRF Severe dz shock, myocarditis ARDS, cerebral or gastrointestinal bleeding, ruptured spleen, hepatic failure, Jarisch–Herxheimer reactions & opportunistic typhoid or other bacterial infections. Pregnant women are at high risk of aborting and perinatal mortality is high.
#LBRF Infection is by inoculation of body louse feces by scratching. Relapse F due to antigenic variation of borrelial outer-membrane lipoprotein. High fever, rigors, headache start abruptly 2-18d post exposure. Petechial rash, epistaxis, jaundice, hepatosplenomegaly common.
#LBRF fascinating history from Hippocrates’ times, through 6th century ‘Yellow Plague’, to epidemics in 🇮🇪 🏴 🏴 in 19th century & 2 large Afro-Middle Eastern pandemics in 20th century. An endemic focus persists in Ethiopia & Horn of Africa. Since 2015, re-emerging in refugees
#borrelia #recurrentis of louse borne relapsing fever #LBRF (seen E Africa, crowded condition, lice)
Ddx #spirochetes in the blood
tick borne relapsing fever #TBRF
(Tick borne, wooded cabins Colorado/Utah)
louse borne relapsing fever #LBRF #borrelia #recurrentis
ddx #IDsky
falciparum malaria
yellow fever
other Viral Hemorrhagic F as Rift Valley Fever
viral hepatitis
rickettsial infection
Trench fever (Bartonella quintana
typhoid
#LBRF can be treated with a single dose of intramuscular penicillin or a single dose of a tetracycline. Patients should be observed for a Jarisch-Herxheimer reaction after treatment
#LBRF Severe dz shock, myocarditis ARDS, cerebral or gastrointestinal bleeding, ruptured spleen, hepatic failure, Jarisch–Herxheimer reactions & opportunistic typhoid or other bacterial infections. Pregnant women are at high risk of aborting and perinatal mortality is high.
louse borne relapsing Fever #LBRF by inoculation of body louse feces by scratching. Relapse F due to antigenic variation of borrelial outer-membrane lipoprotein. ⬆️F, rigors, headache start abruptly 2-18d postexposure. Petechial rash, epistaxis, jaundice, hepatosplenomegaly common.
