Slide projected in a conference room showing two possible functional states of microglia: "Inflammatory" and "Resolving." Their effects are in a list, such as immune cell activation and demyelination in the inflammatory state, and debris clearance and myelin repair in the resolving state.
Today was the last day of the course, focused on the dual role of microglia. Its “foamy” phenotype, after phagocytosing damaged myelin, becomes proinflammatory. The purinergic receptor P2X4 was highlighted, as well as the potential of drugs like ivermectin to modulate its response #MS_UIMP25