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Slide projected in a conference room showing two possible functional states of microglia: "Inflammatory" and "Resolving." Their effects are in a list, such as immune cell activation and demyelination in the inflammatory state, and debris clearance and myelin repair in the resolving state.

Slide projected in a conference room showing two possible functional states of microglia: "Inflammatory" and "Resolving." Their effects are in a list, such as immune cell activation and demyelination in the inflammatory state, and debris clearance and myelin repair in the resolving state.

Today was the last day of the course, focused on the dual role of microglia. Its “foamy” phenotype, after phagocytosing damaged myelin, becomes proinflammatory. The purinergic receptor P2X4 was highlighted, as well as the potential of drugs like ivermectin to modulate its response #MS_UIMP25

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Dr. María Villar pointing at a presentation slide during her talk on immunosenescence. The slide shows diagrams of the brain and thymus across different life stages. The room features blue curtains and a decorative ceiling.

Dr. María Villar pointing at a presentation slide during her talk on immunosenescence. The slide shows diagrams of the brain and thymus across different life stages. The room features blue curtains and a decorative ceiling.

A group of five young participants smiling outdoors with the sea in the background, enjoying a sunny moment near the Palacio de la Magdalena in Santander.

A group of five young participants smiling outdoors with the sea in the background, enjoying a sunny moment near the Palacio de la Magdalena in Santander.

Second day at #UIMP, discussing aging in #MS: biomarkers of axonal damage #NfL and inflammation #GFAP, and the impact of immunosenescence with experts like María Villar. We also had a moment to enjoy a bit of sunshine around the Palacio de la Magdalena, Santander #MS_UIMP25

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Conference room at the Menéndez Pelayo International University (UIMP), featuring a large screen displaying the UIMP logo, a wooden table in the foreground, notebooks, and several institutional flags in the background.

Conference room at the Menéndez Pelayo International University (UIMP), featuring a large screen displaying the UIMP logo, a wooden table in the foreground, notebooks, and several institutional flags in the background.

Seminar in progress at the Menéndez Pelayo International University (UIMP), with participants seated around a large wooden conference table and others joining remotely via video call, displayed on a large screen at the front of the room.

Seminar in progress at the Menéndez Pelayo International University (UIMP), with participants seated around a large wooden conference table and others joining remotely via video call, displayed on a large screen at the front of the room.

Third time attending this multiple sclerosis #MS meeting at #UIMP, this year focusing on the new diagnostic criteria, aging, and the role of microglia. #MS_UIMP25

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