Disrupted macrophage metabolic adaptation and function drive senescence-induced decline in vertebrate regeneration

Proud to contribute to this (Yes!) #Telomere study by Farida Djouad team. Morpholinos against zebrafish #TRF2 induce macrophage #senescence and block fin regeneration. #Parabiosis, #MacrophageTracking & #Transcriptomics show #p16-high, and low pro-inflammation.
Go Fish! 🐟🐟🐟
www.thno.org/v15p7308.htm