A diagram illustrating the link between OGID syndromes and mouse models. A human silhouette labelled “OGID syndromes” lists ASD, ID, Overgrowth, Epilepsy, and Distinctive facial appearance. An arrow points to a mouse labeled “Mouse model,” branching into SS, MALNS, and TBRS models, each with a table of behavioural and neurological traits.

Atterton et al. discuss the similarities & differences of certain overgrowth-intellectual disability disorders & explore future approaches to ameliorate some of the unmet clinical needs of patients with #OGID.

doi.org/10.1242/dmm....

#SotosSyndrome, #MalanSyndrome #Tatton-Brown-RahmanSyndrome