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Migraine - atypical clinical presentations and the most common diagnostic challenges INTRODUCTION: Migraine is the most common neurological disorder worldwide. However, despite its high prevalence and clear diagnostic criteria, migraine is frequently underdiagnosed or misidentified as other primary or secondary conditions.

Migraine - atypical clinical presentations and the most common diagnostic challenges
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📚 Source: Neurologia i neurochirurgia polska
👤 Creator: Marta Waliszewska-Prosół
📅 Date: 2026-04-07

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Long-term air pollution exposure and incident migraine in middle aged and older adults: A population-based study CONCLUSIONS: Long-term exposure to PM10 and PM2.5 was found to be associated with increased migraine risk in the middle-aged and older adult Chinese population. Black carbon, sulfate, and organic matter may be the primary contributors to the adverse effects of PM2.5 on migrain...

Long-term air pollution exposure and incident migraine in middle aged and older adults: A population-based study
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📚 Source: Headache
👤 Creator: Panpan Zhang et al.
📅 Date: 2026-04-07

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UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Migraine CONCLUSION: Findings indicate utility of CBMPs for migraine, but randomized controlled trials are required to establish causation.

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Migraine
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📚 Source: Brain and behavior
👤 Creator: Lennon Hooper et al.
📅 Date: 2026-04-07

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Gut microbiota 16S rRNA profiling with plasma and urine metabolomics in vestibular migraine CONCLUSIONS: In this exploratory multi-omics study, VM patients showed distinct gut microbiota composition compared to M and HC, particularly at the genus level. Plasma metabolomics revealed alterations in pyruvate and amino acid metabolism pathways, suggesting possible energy...

Gut microbiota 16S rRNA profiling with plasma and urine metabolomics in vestibular migraine
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📚 Source: Frontiers in neurology
👤 Creator: Qijun Yu et al.
📅 Date: 2026-04-06

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Sex-specific orchestration of morphometric similarity networks in children and adolescents with migraine BackgroundMigraine accounts for most primary headaches in children and adolescents and is related to cortical and connectivity changes. However, the underlying mechanisms remain unclear. Morphometric similarity mapping has not yet been applied to children and adolescents with ...

Sex-specific orchestration of morphometric similarity networks in children and adolescents with migraine
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📚 Source: Cephalalgia : an international journal of headache
👤 Creator: Laura Papetti et al.
📅 Date: 2026-04-06

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Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study BACKGROUND AND OBJECTIVES: To examine the association between genetic risk of migraine and post-traumatic headache (PTH) in children.

Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study
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📚 Source: Neurology. Genetics
👤 Creator: Serena L Orr et al.
📅 Date: 2026-04-06

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Migraine in pediatric population: the role of biochemical markers No abstract

Migraine in pediatric population: the role of biochemical markers
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📚 Source: The journal of headache and pain
👤 Creator: Gabriele Monte et al.
📅 Date: 2026-04-04

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Migraine across the menopausal transition and beyond: A narrative review CONCLUSIONS: Migraine during the menopausal transition reflects the interplay between hormonal dynamics and systemic health. Management requires balancing efficacy with vascular and metabolic safety while incorporating patient preferences. Evidence gaps include the lack of tri...

Migraine across the menopausal transition and beyond: A narrative review
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📚 Source: Headache
👤 Creator: Tal Friedman Korn et al.
📅 Date: 2026-04-04

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Beyond concealment: Translating placebo research into migraine care No abstract

Beyond concealment: Translating placebo research into migraine care
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📚 Source: Headache
👤 Creator: Julian Kleine-Borgmann et al.
📅 Date: 2026-04-04

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Randomized controlled trial of intravenous dexamethasone to prevent relapse in the treatment of migraine in a pediatric emergency department CONCLUSIONS: In this small clinical trial of children and adolescents with acute migraine attack treated in the ED, adjunctive dexamethasone did not reduce relapse rates nor improve functional outcomes compared with placebo. Although limited by low statistical power, these fin...

Randomized controlled trial of intravenous dexamethasone to prevent relapse in the treatment of migraine in a pediatric emergency department
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📚 Source: Headache
👤 Creator: Geneviève Tourigny-Ruel et al.
📅 Date: 2026-04-04

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Integrative Migraine Management Within a Healthcare System Part 2: Behavioral, Complementary and Neuromodualtion Approaches Migraine is a prevalent and disabling neurological condition that benefits from multimodal care. While a growing number of migraine therapies have become available, migraine remains the leading cause of disability among adults under the age of 50. The unmet burden of migraine ...

Integrative Migraine Management Within a Healthcare System Part 2: Behavioral, Complementary and Neuromodualtion Approaches
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📚 Source: The American journal of medicine
👤 Creator: Robert Alan Bonakdar et al.
📅 Date: 2026-04-04

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Sensitivity and specificity of the video head impulse test in the diagnosis of vestibular migraine - A systematic review and meta-analysis CONCLUSION: 43% of VM patients exhibited abnormalities in vHIT. The test demonstrated low sensitivity and high specificity to detect VM.

Sensitivity and specificity of the video head impulse test in the diagnosis of vestibular migraine - A systematic review and meta-analysis
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📚 Source: Brazilian journal of otorhinolaryngology
👤 Creator: Francisco Campelo da Fonseca Neto et al.
📅 Date: 2026-04-03

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Can rimegepant stop symptoms of a migraine attack in people who have not found triptans to work well or are not recommended to use triptans? A plain language summary of a clinical study No abstract

Can rimegepant stop symptoms of a migraine attack in people who have not found triptans to work well or are not recommended to use triptans? A plain language summary of a clinical study
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📚 Source: Pain management
👤 Creator: Messoud Ashina et al.
📅 Date: 2026-04-03

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State-specific disruptions of dynamic functional connectivity in young migraine without aura: a hidden Markov model approach CONCLUSIONS: Young MWoA patients exhibit a dual-mode dysfunction in brain dynamics: heightened external vigilance (State 7) and impaired segregation of internal-external processing (State 9), accompanied by instability in baseline sensorimotor configurations. Prolonged dwellin...

State-specific disruptions of dynamic functional connectivity in young migraine without aura: a hidden Markov model approach
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📚 Source: Frontiers in neuroscience
👤 Creator: ChunYang Xu et al.
📅 Date: 2026-04-03

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Cervical vestibular evoked myogenic potential asymmetry, but not amplitude, differentiates vestibular migraine during prolonged unidirectional visual motion CONCLUSION: Prolonged unidirectional visual stimulation does not significantly affect cVEMP amplitude responses in VM, limiting its value as a differential diagnostic tool. The need to further explore asymmetry and interaural/interhemispheric sensory integration in VM is under...

Cervical vestibular evoked myogenic potential asymmetry, but not amplitude, differentiates vestibular migraine during prolonged unidirectional visual motion
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📚 Source: Frontiers in neurology
👤 Creator: Elvira Cortese et al.
📅 Date: 2026-04-03

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ABO blood group distribution in migraine patients; the relationship of phenotypes with migraine subtypes, clinical features, and white matter lesions: a retrospective case-control study No abstract

ABO blood group distribution in migraine patients; the relationship of phenotypes with migraine subtypes, clinical features, and white matter lesions: a retrospective case-control study
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📚 Source: BMC neurology
👤 Creator: Ferhat Kilicaslan et al.
📅 Date: 2026-04-03

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Efficacy and safety of rimegepant in Chinese women with pure menstrual migraine: a retrospective observational study No abstract

Efficacy and safety of rimegepant in Chinese women with pure menstrual migraine: a retrospective observational study
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📚 Source: BMC neurology
👤 Creator: Wenlu Ye et al.
📅 Date: 2026-04-03

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Alterations of static and dynamic functional connectivity of the nucleus accumbens subregions may be associated with chronic process of migraine: a resting-state fMRI study No abstract

Alterations of static and dynamic functional connectivity of the nucleus accumbens subregions may be associated with chronic process of migraine: a resting-state fMRI study
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📚 Source: The journal of headache and pain
👤 Creator: Geyu Liu et al.
📅 Date: 2026-04-03

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Plasma proteomics identifies proteins and pathways associated with incident migraine in 50,668 adults No abstract

Plasma proteomics identifies proteins and pathways associated with incident migraine in 50,668 adults
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📚 Source: The journal of headache and pain
👤 Creator: Yanggang Hong et al.
📅 Date: 2026-04-03

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The Association Between Migraine and Type 2 Diabetes Mellitus: A Narrative Review Migraine is a prevalent disabling neurovascular condition with a high burden on society. The association between migraine and metabolic disorders, including type 2 diabetes mellitus (T2DM), is unclear. In this manuscript, we reviewed the association between migraine and T2DM. ...

The Association Between Migraine and Type 2 Diabetes Mellitus: A Narrative Review
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📚 Source: International journal of preventive medicine
👤 Creator: Faraidoon Haghdoost et al.
📅 Date: 2026-04-02

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Percutaneous Closure of Patent Foramen Ovale is Associated With Improvement of Migraine CONCLUSION: Percutaneous PFO closure significantly improved migraines by reducing both frequency and severity, supporting a potential association between PFO and migraine.

Percutaneous Closure of Patent Foramen Ovale is Associated With Improvement of Migraine
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📚 Source: Reviews in cardiovascular medicine
👤 Creator: Xiao-Ming Ge et al.
📅 Date: 2026-04-02

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Molecular triggers of migraine aura: A systematic review of human pharmacological provocation studies BackgroundMigraine aura reflects transient neurological disturbances attributed to cortical spreading depolarization (CSD), yet the upstream molecular events that promote or precipitate this phenomenon remain uncertain. Human pharmacological provocation models provide a contro...

Molecular triggers of migraine aura: A systematic review of human pharmacological provocation studies
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📚 Source: Cephalalgia : an international journal of headache
👤 Creator: Zahra Hakimzadeh et al.
📅 Date: 2026-04-02

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Evaluation of the effectiveness and safety of anti-CGRP monoclonal antibodies in patients with migraine and autoimmune diseases: IMMUNO-CGRP study CONCLUSIONS: Our study shows that anti-CGRP treatments are effective and safe for patients with migraine regardless the presence of autoimmune diseases, although an increased treatment response in patient without autoimmune disorders compared to patients with autoimmune disord...

Evaluation of the effectiveness and safety of anti-CGRP monoclonal antibodies in patients with migraine and autoimmune diseases: IMMUNO-CGRP study
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📚 Source: Headache
👤 Creator: María Clara García-Castillo et al.
📅 Date: 2026-04-02

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Oxidative Stress and Mitophagy in Rats With Nitroglycerin/Inflammatory Soup-Induced Migraine: A Comparative Study CONCLUSION: NTG/IS administration comparatively decreased the mechanical threshold, increased the level of oxidative stress, and decreased the level of mitophagy in the trigeminal nucleus caudalis in migraine rats.

Oxidative Stress and Mitophagy in Rats With Nitroglycerin/Inflammatory Soup-Induced Migraine: A Comparative Study
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📚 Source: Pain research & management
👤 Creator: Wen-Xiu Sun et al.
📅 Date: 2026-04-01

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Comparison of brain volumes in episodic and chronic migraine using automated whole-brain volumetry Migraine chronification is associated with increased clinical burden, yet structural neuroimaging findings remain inconsistent. We compared global and regional brain volumes among patients with episodic migraine (EM), chronic migraine (CM), and healthy controls (HC) using an a...

Comparison of brain volumes in episodic and chronic migraine using automated whole-brain volumetry
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📚 Source: Frontiers in neurology
👤 Creator: Halil İbrahim Akçay
📅 Date: 2026-04-01

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Optimizing Chronic Migraine Care: The Impact of Advanced Practice Nurse Involvement in OnabotulinumtoxinA Administration CONCLUSION: The involvement of advanced practice nurses in OnabotA administration decreased the time interval between infiltrations and improved adherence to the PREEMPT protocol. These findings highlight the APN's role in optimizing patient care.

Optimizing Chronic Migraine Care: The Impact of Advanced Practice Nurse Involvement in OnabotulinumtoxinA Administration
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📚 Source: Revista de neurologia
👤 Creator: Eulalia Gine-Cipres et al.
📅 Date: 2026-03-31

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Pediatric Migraine Aura Status and Cortical Laminar Necrosis: A Clinical Case and a Narrative Review CONCLUSIONS: This clinical case is interesting due to the uncommon correlation between cortical laminar necrosis and migraine with aura (MA), the pediatric presentation, the location of hypoperfusion and the atypical progression of the migraine aura. We have reported a narrati...

Pediatric Migraine Aura Status and Cortical Laminar Necrosis: A Clinical Case and a Narrative Review
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📚 Source: Revista de neurologia
👤 Creator: Federica Cernigliaro et al.
📅 Date: 2026-03-31

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Distinguishing Interictal Neuromagnetic Activity in Migraine With and Without Aura: A Resting-State Magnetoencephalography Study CONCLUSIONS: This study revealed the distinct neuromagnetic signatures of MwA and MwoA, linking specific connectivity patterns to clinical features. These findings could potentially support the development of subtype-specific, targeted neuromodulation therapies for migraine.

Distinguishing Interictal Neuromagnetic Activity in Migraine With and Without Aura: A Resting-State Magnetoencephalography Study
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📚 Source: Journal of integrative neuroscience
👤 Creator: Di Wu et al.
📅 Date: 2026-03-31

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The relationship between triglyceride levels and medication overuse headache in patients with chronic migraine CONCLUSIONS: Elevated TG levels may be associated with MOH in patients with CM, underscoring their importance in the diagnostic evaluation and therapeutic management of patients with CM.

The relationship between triglyceride levels and medication overuse headache in patients with chronic migraine
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📚 Source: Journal of oral & facial pain and headache
👤 Creator: Hailin Liu et al.
📅 Date: 2026-03-31

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Clinical predictors of propranolol responsiveness in pediatric migraine: a prospective observational study CONCLUSIONS: Both propranolol and structured behavioral therapy effectively reduce migraine-related disability and pain in pediatric patients, yielding comparable proportional improvements. The identification of key clinical and biochemical predictors supports a personalized t...

Clinical predictors of propranolol responsiveness in pediatric migraine: a prospective observational study
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📚 Source: Journal of oral & facial pain and headache
👤 Creator: Müge Baykan et al.
📅 Date: 2026-03-31

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