Structural Insights into L-Type Voltage-Gated Ca2+ Channel (CaV1.2) Activation by CaBP1 The L-type voltage-gated Ca2+ channel (CaV1.2) controls gene expression, cardiac function, and neuronal excitability. Mutations in CaV1.2 that disrupt channel function are implicated in cardiac arrhyt...

The team went to the #biophysical and #modeling side to understand how the CaBP1 protein regulates L-type channels. Great collab with Jim Ames, Hell Lab & #MnMLab

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pubs.acs.org/doi/10.1021/...