Researchers at Genentech published an interesting preprint describing the discovery of a #monovalent electrophilic #degrader of SMARCA2/4 that acts as a #molecularglue mediating an interaction with "frequent hitter" E3 ligase FBXO22.
www.biorxiv.org/content/10.1...
Reactivity Study of the Bis(phosphine)-Stabilized Antimony(I) Cation | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Yildiz, Majumdar, and co-workers @InorgChem #antimony #monovalent #bisphosphine #nucleophilicity
Effectiveness of Original #Monovalent and #Bivalent #COVID-19 #Vaccines Against COVID-19-Associated #Hospitalization and #Severe In-Hospital #Outcomes Among Adults in the United States, September 2022-August 2023
https://buff.ly/3ZcX8ok
#CovidVaccine7x #ModernaXBB15 #Monovalent DONE!!! ๐๐๐๐๐๐๐๐ช๐