MORF4-related gene on chromosome 15 (MRG15) interacts with MyoD to regulate histone acetylation and transcription of myogenic genes

Cell Regen Research | Even spaceflight-like aging reveals MRG15 as a key player 🧩 in muscle stem cell regeneration! Its decline in aged/injured MuSCs impairs regeneration via MyoD disruption & histone changes.
#MuscleRegeneration #StemCells
🔗 Full paper at: doi.org/10.1186/s136...

Extracellular vesicles derived from neonatal mouse skeletal muscle accelerate muscle regeneration and reduce adipocyte infiltration and collagen deposition in vivo

Cell Regen Research | Speed up muscle repair! 🩹 Neonatal muscle extracellular vesicles activate satellite cells, boost regeneration, and reduce fibrosis/fat infiltration in glycerol injury models. #MuscleRegeneration #StemCells

🔗 Full paper at: doi.org/10.1186/s136...

New Treatment Option (SAT-3247) for Duchenne Muscular Dystrophy Shows Promise in Early Phase Trial Wildon Farwell, MD, CMO at Satellos, discusses the safety and efficacy of SAT-3247, a new treatment option for Duchenne muscular dystrophy.

In a recent @CheckRare feature, Satellos CMO Dr. Wildon Farwell discusses the science behind SAT-3247 and how restoring the #muscleregeneration process could offer a new therapeutic approach for people living with #Duchenne #FSHD $msclf $mscl Watch the interview checkrare.com/new-treatmen...

Schneider et al. found that hyperbaric oxygen therapy promotes muscle regeneration in preclinical models of skeletal muscle injury, with early initiation being crucial for optimal outcomes.
#OpenAccess in #MedGasRes: doi.org/10.4103/mgr....
#HBOT #MuscleInjury #MuscleRegeneration

📣 The paper is out!!

In this paper we tackled 2 major bottlenecks of cell therapy, namely how to increase the yield of progenitors in vitro and, by serendipity, how to mature them to an higher developmental stage.

#muscle #stemcelltherapy #muscleregeneration

www.cell.com/stem-cell-re...

The third @change-ecm.bsky.social abstract comes from Michal Tamáš who is researching skeletal muscle regeneration under the supervision of Prof Bonaldo at the Università degli Studi di Padova. To find out more, drop Michal a line: www.linkedin.com/in/michaltamas

#MSCA_DN #muscleregeneration #colVI

Intramuscular fat: Muscle “marbling” is good in steak but harmful in our bodies – BioNews Central Intramuscular fat not only indicates poor health and various diseases but also actively impairs muscle healing and function by physically blocking muscle regeneration. ...

#IntramuscularFat not only indicates #PoorHealth and #disease but also directly hinders #MuscleRepair and function by physically obstructing regeneration.
#MuscleFunction #MuscleRegeneration

MicroRNA-33 inhibition improves muscular dystrophy symptoms by boosting skeletal muscle regeneration, offering a promising therapeutic avenue. #MuscleRegeneration #Duchenne #MicroRNA

#just published in @embomolmed.org

www.embopress.org/doi/full/10....

Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles - Nature Communications Lack of muscle stem cell targeting limits the treatment of muscular dystrophies. Here, the authors describe a platform based on functionalized gold nanoparticles that allows selective delivery of ther...

Aptamer-conjugated gold nanoparticles (AuNPs) enhance oligonucleotide delivery to muscle stem cells for muscular dystrophy therapy via targeted release. #MuscleRegeneration #Innovation PMID:39794309, Nat Commun 2025, @NatureComms doi.org/10.1038/s414...