Genome-first approach data GATA2, RUNX1, ETV6 defines population prevalence of pathogenic variants. Age at myeloid malignancy w/ DDX41 similar to age in general population but risk higher. #ASH24 #Leukemia
Dr McReynolds #NCI_ClinicalGenetics

Saving the best (but I “may” be biased) for last in #ASH24 germline workshop - Dr. Maryam Rafati from #NCI_ClinicalGenetics presenting on heterozygous #DNA repair gene variants & #HCT outcomes. MUTYH carriers had poorer outcomes if received #TBI
Collab w/ #CIBMTR