A single non-coding SNP in FPGS modulates folate drug efficacy in acute lymphoblastic leukemia: data-driven exploration and experimental validation - Molecular Biomedicine For over 70 years, methotrexate (MTX) has remained a first-line chemotherapeutic agent for acute lymphoblastic leukemia (ALL), playing a pivotal role in maintenance therapy. Understanding the genetic ...

#Research
A single non-coding SNP in FPGS modulates folate drug efficacy in acute lymphoblastic leukemia: data-driven exploration and experimental validation doi.org/10.1186/s435...

#Folylpoly #glutamate #synthetase #NoncodingSNP #GeneticVariant #AcuteLymphoblasticLeukemia