Environmental Toxicants, including Pesticides, Linked to Parkinson’s Disease - Beyond Pesticides Daily News Blog A review in Lancet Neurology provides a clear snapshot of the state of scientific understanding of Parkinson’s disease and how medicine and policy could be improved by shifting focus to the primary causes of the disease, namely environmental toxicants, and to emphasize prevention rather than devoting resources only to treatments and a cure.

A review, led by Ray Dorsey, M.D. of University of Rochester, provides a clear snapshot of how medicine and policy could be improved by shifting focus to primary causes of #Parkinson's, namely environmental #toxicants. #pesticides #paraquat #rotenone #organochlorine ➡️ Blog: https://ow.ly/qTbG50Xl5CR

Modes of Action of Persistent Pesticides Documented, with Ongoing Poisoning and Multigenerational Effects - Beyond Pesticides Daily News Blog A new study raises concerns about exposure to organochlorine pesticides (OCPs) and the disruption they cause to biological systems.

#Organochlorine #pesticides' modes of action & biological effects documented by French & Kazakhstani institutions in new study as residual exposure continues to raise alarms. @Univ_Lorraine @KazNU_official #legacy #endocrinedisruption #ddt #hch #cld Blog:

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Pesticide Use Again Linked to Inflammatory Bowel Disease, This Time Among Applicators and Their Spouses - Beyond Pesticides Daily News Blog A recent study finds a significant correlation between exposure to pesticides and an elevated risk of inflammatory bowel disease (IBD).

A @NIEHS & @NCIEpiTraining research team finds a significant correlation between exposure to several #organochlorine insecticides—as well as #organophosphate insecticides & herbicides—and an elevated risk of inflammatory bowel disease (#IBD). ⚠︎ Blog:

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A research team at @uofl links acute exposure to #chlordane, an #organochlorine #insecticide, to toxicant-associated steatosis (fat retention) #liver disease (TASLD) in mice with sex-specific, #endocrine, & metabolic effects. Blog:

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Pesticide Exposure Driving Liver Disease through Hormone Disrupting Mechanisms - Beyond Pesticides Daily News Blog (Beyond Pesticides, July 21, 2022) Research published in Scientific Reports finds an association between the increasing emergence of nonalcoholic fatty liver disease (NAFLD) and exposure to endocrine (hormone) disrupting chemicals, like organochlorine pesticides (OCPs). It is well-known that traces of legacy (past-use) pesticides, like organochlorines, remain in the environment for decades—possibly centuries, post-final application, as OCPs have greater chemical stability and gradual attenuation. However, these chemicals have profound adverse impacts on human health, especially on the endocrine system. Obesity, insulin resistance, type 2 diabetes, and elevated liver enzyme resulting from endocrine disruption contribute to NAFLD and can lead to liver cirrhosis. Although some, but not all, manufacturing and use of specific OCPs have declined in the U.S., OCPs remain a global issue, as much of the developing world still reports usage. Considering the lack of studies on OCP-induced endocrine disruption and NAFLD, research like this highlights the need to understand the underlying mechanisms that contribute to growing endocrine disease incidents.   The study determined that there is an association between OCP exposure and NAFLD using the fatty liver index (FLI), a predictor of lipid (fat) accumulation in the liver. The researcher collected blood serum to measure the concentration of OCPs, specifically evaluating detectable […]

Exposure to #endocrine-disrupting chemicals like #organochlorine #pesticides can lead to #nonalcoholicfattyliverdisease #NAFLD. Legacy chemical traces stay in the #environment for decades, maybe centuries. #liverdisease #cirrhosis #fattyliver #publichealth

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Study Identifies the Presence of Organochlorine Pesticides among South China Sea Coral Reefs - Beyond Pesticides Daily News Blog (Beyond Pesticides, August 12, 2021) A recent study published in Chemosphere identifies the concentration, consequences, and potential sources of 22 organochlorine pesticides (OCPs) among corals in the South China Sea (SCS) for the first time. SCS corals exhibit a higher affinity toward bioaccumulation of OCPs, which are legacy persistent organic pollutants (POPs) under the Stockholm Convention—a global treaty to eliminate POPs. The study finds the distribution of OCPs in coral tissue matches that of the surrounding oceanic air samples. Hence, atmospheric concentrations of OCPs—influenced by continental air masses—migrate from the atmosphere to seawater through gas exchange. Coral reefs are one of the largest ecosystems in the ocean, sustaining marine biodiversity and providing many goods and services. However, living coral populations are rapidly declining due to ocean acidification, oceanic warming, habitat destruction, and pollution from human activity across the globe. From rare corals off the coast of Florida to well-established hard corals in the Great Barrier Reef, these communal organisms are sensitive to various environmental stressors that threaten biodiversity. Although several studies demonstrate the volatile, toxic nature of POPs, much less research evaluates the impact POPs have on biodiversity over time. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and […]

South #China Sea corals exhibit a higher affinity toward bioaccumulation of #organochlorine #pesticides, which are legacy persistent organic pollutants (POPs) under the Stockholm Convention—a global treaty to eliminate POPs. #oceans #coralreefs #pollution

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