Solubilization and Selective Integrin-targeted Delivery of Polycyclic Aromatic Hydrocarbons with Amphiphilic α-Helices | ChemRxiv Large polycyclic aromatic hydrocarbons exhibit attractive photophysical properties for imaging and phototherapy applications. However, their biomedical application remains limited by their poor aqueous solubility. We report that the amphiphilic α-helical ...Structure of a representative conformation of the 1/NSPr complex extracted from the MD run. A light blue alpha-helical protein structure wraps around a central, gray graphene-like nanosheet (represented in a space-filling van der Waals model).

Happy to share our last preprint! We’ve repurposed the amphiphilic alpha-helical peptide NSPr, originally designed for membrane protein stabilization, as a biocompatible dispersant for large nanographenes (NGs).

chemrxiv.org/doi/full/10....

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Promotional graphic showing the publications graphical abstract of an M60L60 capsid structure.

💡Expanding the foundations of peptide engineering.

In this work published in @cellpress.bsky.social, researchers synthesized a new, self-assembled capsid-like structure, providing a novel strategy to construct large metal-peptides.

🔗 ccdc-info.com/45JU9r6.

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