Northamptonshire police apologise to Harry Dunn’s family for failures investigating his death Scathing review finds ‘significant shortcomings’ in force’s investigation of teenage motorcyclist’s death and how case was handled

WHAT GOOD IS AN APOLOGY WHEN THE OPPORTUNITY FOR JUSTICE HAS BEEN LOST DUE TO POLICE INCOMPETENCE? #PLOD

www.theguardian.com/uk-news/2025...

Greater Manchester Police sorry for arresting woman who said she was raped The woman, who had said she had been raped, was arrested over social media posts she had made.

Manchester Plod messed up victim’s case, DNA & CCTV lost.
#Plod

www.bbc.co.uk/news/article...

Taking Care of History: Toward a Politics of Provenance Linked Open Data in Museums | The Art Institute of Chicago An account of the limitations of museums’ current approaches to presenting provenance data digitally that advocates for adopting a linked open data (LOD) approach.

In "Taking Care of History: Toward a Politics of Provenance Linked Open Data in Museums" (2022), we have laid out a detailed vision for how museums should begin addressing the transformation of their provenance records into PLOD - Provenance Linked Open Data.

#DigitalProvenance #PLOD

Holocaust survivor, 87, questioned by police after laying flowers during Gaza protest Stephen Kapos was among nine people called in over 18 January pro-Palestine protest

British police being inept again.
#Plod

www.independent.co.uk/news/uk/home...

Balaclava gangs with hammers targeting cyclists in London's Regent's Park Many cyclists said they were threatened with hammers, machetes and knives before their bikes were stolen.

In central London, and the cops say they can’t stop it as they don’t start work before 8am.
#Plod

metro.co.uk/2025/02/24/b...

Didcot Power Station probe reaching 'latter stages', police say It has been nine years since a boiler house collapse killed four demolition workers at the site.

9+ years and the investigation has still not finished.
If a police officer had died you can bet it would have been investigated quicker.

#PLOD!

www.bbc.co.uk/news/article...

As any woman in the back of a locked taxi knows, Sam Kerr should never have been brought to court | Suzanne Wrack The Matildas and Chelsea forward won’t be proud of the footage of her in a police station. But her acquittal underlines that the charges and court battle that followed were a waste of time and money

#Plod

www.theguardian.com/football/202...

Stalking: Police 'missed red flags' in neo-Nazi Callum Parslow Stalking victims were told a far-right attacker

All complaints received against the Police will be ignored. #Plod

www.bbc.co.uk/news/article...

Southport attack: families not told for six months about killer’s Prevent referrals Police knew Axel Rudakubana had been referred three times after his arrest last July

British Police have a lot to answer for, mostly because they prejudiced and incompetent. #Plod

www.theguardian.com/uk-news/2025...

How are these people not being arrested for #conspiracy ? They are just out for themselves. If you are #jso or other #climate activist you would be having #plod knocking on your door #doublestandards #oneruleforthem
#climatecrisis
#climateemergency

Identification of Regulatory Molecular “Hot Spots” for LH/PLOD Collagen Glycosyltransferase Activity Hydroxylysine glycosylations are post-translational modifications (PTMs) essential for the maturation and homeostasis of fibrillar and non-fibrillar collagen molecules. The multifunctional collagen lysyl hydroxylase 3 (LH3/PLOD3) and the collagen galactosyltransferase GLT25D1 are the human enzymes that have been identified as being responsible for the glycosylation of collagen lysines, although a precise description of the contribution of each enzyme to these essential PTMs has not yet been provided in the literature. LH3/PLOD3 is thought to be capable of performing two chemically distinct collagen glycosyltransferase reactions using the same catalytic site: an inverting beta-1,O-galactosylation of hydroxylysines (Gal-T) and a retaining alpha-1,2-glucosylation of galactosyl hydroxylysines (Glc-T). In this work, we have combined indirect luminescence-based assays with direct mass spectrometry-based assays and molecular structure studies to demonstrate that LH3/PLOD3 only has Glc-T activity and that GLT25D1 only has Gal-T activity. Structure-guided mutagenesis confirmed that the Glc-T activity is defined by key residues in the first-shell environment of the glycosyltransferase catalytic site as well as by long-range contributions from residues within the same glycosyltransferase (GT) domain. By solving the molecular structures and characterizing the interactions and solving the molecular structures of human LH3/PLOD3 in complex with different UDP-sugar analogs, we show how these studies could provide insights for LH3/PLOD3 glycosyltransferase inhibitor development. Collectively, our data provide new tools for the direct investigation of collagen hydroxylysine PTMs and a comprehensive overview of the complex network of shapes, charges, and interactions that enable LH3/PLOD3 glycosyltransferase activities, expanding the molecular framework and facilitating an improved understanding and manipulation of glycosyltransferase functions in biomedical applications.

New #publication! A summary of many years of work focusing on characterization of #collagen #lysylhydroxylase / #PLOD #glycosyltransferase activity. @AIRC_it @ArmeniseHarvard #mizutanifoundation #EUfunded @MSCActions @RegLombardia. Out now in @IJMS_MDPI. https://www.mdpi.com/1422-0067/24/13/11213#