In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor
🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins
doi.org/10.1101/2025...

Structural basis for the pore-forming activity of a complement-like toxin A detailed mechanism by which a pore-forming toxin forms gigantic membrane pores using structural biology is reported.

Structural basis for the pore-forming activity of a complement-like toxin | Science Advances www.science.org/doi/full/10.... #poreformingtoxins