Had a great time at my first #SBUK24 conference🧬
Thankful I got to present my poster on the effects of spatial resource distribution on the performance of genetic circuits.
Got to attend awesome talks, see amazing posters and discuss with peers working on similar topics!
Great way to start my PhD :)

What I should have done if I was a good supervisor is advertise the posters that Alice, Casey, and Louie brought to #sbuk24

However, I got lots of lovely comments from folks who had chatted to my group #proudPI

I was blown away by the amazing plant synbio that's going on! #sbuk24 #sbuk2024

Reflecting on the two days of #sbuk24 talks on the very slow journey home, I think my favourite was Scott Stacey from Harrison Steel's group.

Lovely demonstration of complexity built from simple biology that needs modelling to fully understand an unexpected result

A wonderful keynote from Jason Chin to round up #SBUK24! Great overview of his work covering development of compressed synthetic genomes and expansion of the genetic code. A great way to round up a fantastic conference. Thank you Biochemical Society!

To close the conference, Jason Chin walks us through reprogramming the genetic code to allow the bioproduction of non-canonical polymers #sbuk24

Now at #SBUK24 we're straight onto Protein and Genome Design session with the first keynote from Dek Woolfson exploring rational and computational protein design and applications in modifying cellular transport

Leopold Parts is scrambling the genome to help understand arrangement, essentiality and function #sbuk24

Andrey Romanyuk has rationally designed proteins capable of forming biocondensates that can fuse to other proteins of interest using a dumbbell structure #sbuk24

Georgie Hau Sorensen introduces a tool for inserting dogtags into proteins to allow more control over binding of accessory proteins e.g. deaminase bound to polymerase #sbuk24

The final session is on protein and genome design, starting with Dek Woolfson. How can we go from some basic chemical understanding of amino acid interactions to build new to nature proteins? #sbuk24

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Rita Dias from beneficial.bio is trying to overcome the reliance on imported reagents and other issues hindering the SynBio space in East Africa. I really want to take the enzyme manufacturing masterclass! #sbuk24

The next session is on responsible research and innovation. Sana Zakaria opens the session by discussing the importance of adequately assessing risk for development of proportionate responses #sbuk24

Fantastic discussions and advice from the Early Career Researcher Careers Panel at #SBUK24. Great to hear stories from pannelist with such diverse career paths.

Engineering Biology CDT students from Bristol and Oxford are attending #SBUK24, with CDT Director Lucia Marucci, & BBI Scientific Manager @synbiosedge.bsky.social

Later today, BBI researchers Dek Woolfson, Andrey Romanyuk, & @georgiehs.bsky.social will speak in the Protein & Genome Design session.

Nice to see the vision for engineering biology from @ukri.org at #SBUK24

A quick update at #SBUK24 from Anne Ferguson-Smith, Executive Chair of @BBSRC on the importance of #EngineeringBiology for the future of UK research and the development of the UK #bioeconomy. It's great to see that UKRI are just as excited about the future of the field as we are!

Ella Thornton is improving proteases using cell free and active learning directed evolution #sbuk24

Yuxin Shen shows the importance of feature representation for sequence-to-expression prediction #sbuk24

The next session of #SBUK24 is AI and Machine Learning. Diego Oyarzún has lead us off with a great keynote highlighting three areas where AI is already advancing #SynBio: sequence-to-expression prediction, low-N molecular drug discovery and optimisation of bacterial growth media

Diego Oyarzun starts the AI/ML session by showing that it's possible to apply ML to SynBio with small data sets #sbuk24

Valeriia Kravchik engineered probiotics to produce butyrate to alleviate chrones disease controlled with an incoherent feed forward circuit #sbuk24

Followed by Jordy Alexis Lerma Escalera sharing his work on temporal genetic control in cell free systems, Scott Stacey on using sponge RNAs for genetic circuit design, and Valeriia Kravchik discussing her work developing a synthetic microbiome as a potential IBD treatment #SBUK24

Oh dear, another left handed DNA. And it's in an EU Doctoral Network logo 😶‍🌫️🙈 #SBUK24 #SBUK2024

Scott Stacey uses sponge RNAs to control synthetic circuits but finds some unexpected resource competition #sbuk24

Jordy Alexis Lerna Escalera demonstrates control over the timing of transcription using toeholds and RNA degrading enzymes #sbuk24

Welcome back to day 2 of Biochemical Society's SynBio UK 2024 #SBUK24 conference! Kicking off the Control Systems session this morning is Harrison Steel with a great run through of the lab's interests - from using microfluidics for directed evolution to fluorescent magnetic and RF sensor development

Day 2 of #sbuk24 starts with a session on control opened by Harrison Steel. Lots of excellent stuff (as usual), from directed evolution in microfluidics to "magnetogenetics"

Great sneak peak of #SBUK24 yesterday at @engbioirc.bsky.social Forum with Kate Adamala and Sean Cutler talks! Sadly missing the conference but following the hashtag here 👀🧬

Tom Irving is manipulating the interactions between plants and fungi using a non-gm approach (chemical that farmers can spray on their crops) #sbuk24