Pharmacokinetics of Inhibitors of Succinyl-CoA:3-Ketoacid CoA Transferase in Sprague–Dawley Rats, and the Effect of a High-Fat Diet - The AAPS Journal Pimozide and PSSI-51 are under study for their potential glucose-lowering effects in type 2 diabetes, through their abilities to inhibit succinyl-CoA:3-ketoacid CoA transferase, the rate-limiting enzy...

Happy to share a new paper we contributed to in collaboration with Dr. Dion Brocks' team @ualberta-pharm.bsky.social studying the #pharmacokinetics of #SCOT_inhibitors we've developed for the potential treatment of #T2D link.springer.com/article/10.1...