Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression - Cell Death Discovery Cell Death Discovery - Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression

How does the #cytokine #Lipocalin-2 (#LCN2) link #bone and #EnergyHomeostasis? With help from Sable Promethion #Metabolic Cages, scientists revealed how LCN2 modulates bone remodeling by driving #ferroptosis & suppressing #Wnt signaling.

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#SLC22A17 #IndirectCalorimetry #Respirometry