#SMIMemberReview

Understanding Predictors of Crohn’s Disease: Determinants of Altered Barrier Function in Pre-Disease Phase of Crohn’s Disease Abstract. The pathogenesis of Crohn’s disease (CD) remains unknown. The current working theory is that genetic susceptibility influences host–microbe inter

Read the latest #SMIMemberReview by Kenneth Croitoru and colleagues on how the CCC-GEM cohort has helped with identifying demographic, serological, and microbiome composition markers associated with an increased risk of #Crohn.

academic.oup.com/jcag/article...

The renaissance of oral tolerance: merging tradition and new insights - Nature Reviews Immunology Oral tolerance describes how the oral administration of harmless antigens (such as dietary proteins) leads to systemic immune unresponsiveness to these antigens. Its failure can lead to conditions suc...

Read the latest #SMIMemberReview by Alan Mowat and Olivier Pabst on oral tolerance in Nature Reviews Immunology. www.nature.com/articles/s41...

The renaissance of oral tolerance: merging tradition and new insights - Nature Reviews Immunology Oral tolerance describes how the oral administration of harmless antigens (such as dietary proteins) leads to systemic immune unresponsiveness to these antigens. Its failure can lead to conditions suc...

Read two excellent #SMIMemberReview from Stephanie Eisen and Allen Mowat on #Allergy and oral tolerance. Read more in JACI Online and Nature Reviews Immunology:
www.nature.com/articles/s41...