#S_pregabalin

Rational design of d-hydantoinase from Pseudomonas aeruginosa for desymmetric synthesis of chiral intermediate for (S)-pregabalin (S)-Pregabalin (S-PGB) is extensively employed in analgesic therapy. One of the current chemical processes used to produce S-PGB involves the Hofmann …

Find out how the production of (R)-3-isobutyl glutaric acid, which is used to obtain the (S)-Pregabalin, can be dramatically improved via enzyme-catalyzed route #S_pregabalin #sustainable_synthesis www.sciencedirect.com/science/arti...