Experimental design and task. Top left: Intracranial electroencephalographic activity, eye and body movements were recorded as participants freely walked around the room. Wall-mounted motion-tracking cameras recorded the position of on-body reflective markers. Participants also wore an eye-tracking headset to monitor saccadic eye movements. A snapshot from the eye-facing camera is shown in the bottom right. For illustrative purposes, an experimenter is shown wearing the full setup. Top right: MRI of an example participant with an implanted RNS System. Purple dots indicate the location of four electrode contacts in the left medial temporal lobe (MTL). The top left inset shows an X-ray used to localize electrode positions. Bottom left: The environment contained 20 visible wall-mounted signs and three invisible circular target locations (0.7 m diameter). At the start of the task, participants freely explored the room to locate the invisible targets; each time a target was reached, an auditory tone signaled success, allowing them to gradually learn and remember these locations through experience. The task then alternated between two conditions: “visually-cued” navigation, during which participants navigated to a wall-mounted sign (e.g., “Blue 3”), and “memory-cued” navigation, during which they recalled and navigated to the previously learned invisible targets (e.g., “T”).
How do MTL theta oscillations relate to eye & body movements during navigation? @suthanalab.bsky.social &co show that #theta power increases during #saccades under memory demands, linking exploratory gaze & planning to memory‑related dynamics during #navigation @plosbiology.org 🧪 plos.io/4dwJhR8