#ShivanMisra

Investigating the pathogenicity of the recessive HNF1A p.A251T variant in monogenic diabetes using iPSC-derived beta-like cells Monogenic diabetes, formerly called Maturity-Onset Diabetes of the Young (MODY), involves single-gene mutations, typically with dominant inheritance, and has been associated with variants in 14 genes....

First post! Our new report with #ShivanMisra and #DieterEgli on a recessive HNF1A variant as modelled in iPS beta cells. From force of nature #InesCherkaoui.
medrxiv.org/cgi/content/...