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And an excellent summary. It's all go in the world of TB treatment!

#ESCMIDGlobal2026 #TBSky #IDSky

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Nice vision by Nicholas Paton for TB treatment in the future.

8 week oral treatment followed by long-acting injectable that could be antimicrobial +/- host-directed.

Definitely a post to come back to in 5-10 years' time!

#ESCMIDGlobal2026 #IDSky #TBSky

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Recent nice paper @lancetrespirmed.bsky.social looked at this: radiolgical changes (not culture) in asymptomatic contacts predictive of risk of TB disease development. PET-CT best but CXR not bad and feasible. @ucltb.bsky.social
www.thelancet.com/journals/lan... #IDSky #TBSky #ESCMIDGlobal2026 (2/2)

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Excellent talk from Hanif Esmail on asymptomatic TB.

Around half of M tuberculosis culture positive patients have no symptoms & probably contributes to transmission.

Who should we offer treatment to?
#TBSky #IDSky #ESCMIDGlobal2026 (1/2)

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Physiological peristaltic-like reactions of the tracheobronchial tree move pulmonary Mycobacterium tuberculosis bacilli into the gastrointestinal tract Medical improvements made upon previous knowledge are colloquially known as standing on the shoulders of giants. Tuberculosis diagnostics have improved since 2006 due to improved microfluidics and…

🚨Publication Alert🚨

Tuberculosis diagnostics have advanced since 2006. As technologies evolve, understanding physiology remains essential to apply these tools to traditional sample collection.

buff.ly/fIhrpzf

Congrats to all contributors👏

#TBSky

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I disagree with the suggestion that 'large clinical trials [do] not work well in complex or highly drug-resistant disease'

I also think personalised medicine will have little role to play in public health management of TB - stratified treatment duration perhaps, but mostly it's a mug's game

#TBSky

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Revisiting tuberculosis diagnostics: progress, pitfalls, and future directions Tuberculosis (TB) continues to pose a significant global health threat, claiming ∼1.25 million lives in 2023 [1]. Timely diagnosis is essential for treatment and transmission control, yet it remains the weakest link in TB care, with millions of cases undetected each year [2].

Revisiting tuberculosis diagnostics: progress, pitfalls, and future directions
#IDSky #TBSky @cmijournal.bsky.social

www.clinicalmicrobiologyandinfection.org/article/S119...

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In February, the four TB Centers of Excellence (COEs) sponsored a postgraduate course on Complex Contact Investigations during the 30th Annual Conference of The Union-North America Region in Philadelphia, PA.

#CurryTBCenter @theunion.org #EndTB #Tuberculosis #GotCurry #TBSky #IDSky

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Register Now for the 30th National TB Conference!

📆 June 8-12, 2026
📍Palm Springs, California
web.cvent.com/event/40b2c9...

@tbcoalitionamerica.bsky.social
#Tuberculosis #EndTB #TBSky #IDSky

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#ICYMI To commemorate #WorldTBDay, last week, Eswatini convened a high‑level TB conference emphasizing coordinated action. A panel moderated by Dr. Debrah Vambe featured TB GAPS’ Mbongeni Dube, who discussed sustainable financing to advance the country’s 2030 TB elimination target. #TBSky

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The Curry International Tuberculosis Center is pleased to announce the availability of the following archived webinar:

The Evolving Landscape of Laboratory Testing for Tuberculosis

www.currytbcenter.ucsf.edu/trainings/ar...

#Tuberculosis #TBSky @aphl.org #GotCurry #CurryTBCenter

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In TB treatment trials, we need both ITT and PP estimates, as we use non inferiority designs for the efficacy endpoint

Removing folk with poor adherence from analysis population may be informative censoring

Shouldn't we be weighting our PP estimates, e.g. IPCW?

@danieljgrint.bsky.social #TBSky

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TB Elimination Heroes - CTCA

Congratulations to the 2026 California TB Elimination Heroes!

ctca.org/tb-heroes/

#Tuberculosis #WorldTBDay #TBSky

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When I started this PhD, we watched TB funding redirected to COVID. As I prepare to finish, we're witnessing the catastrophic dismantling of USAID and NIH funding.

The constant: Mtb killing 1.3 million people annually.

World TB Day reminds us the work continues, regardless of politics.

#TBsky

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Accelerating research and development of new vaccines against tuberculosis: 5-year progress on the global roadmap In 2021, a global tuberculosis vaccine research and development roadmap proposed a series of actions to accelerate the development of new, effective, and affordable vaccines that are urgently needed t...

On World TB Day...
#IDSky #TBSky @thelancetinfdis.bsky.social

www.thelancet.com/journals/lan...

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Just Released! 2025 Provisional Tuberculosis Data Report from the CDC: www.cdc.gov/tb-data/abou...

On March 24, we recognize World TB Day. This annual event commemorates the date Dr. Robert Koch announced his discovery of the bacillus that causes tuberculosis (TB)

#TBSky #WorldTBDay #Tuberculosis

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A fascinating long read for World TB Day #tbsky @stoptb.bsky.social @madhupai.bsky.social @treatmentactiongroup.org @tomscriba.bsky.social

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New review article

Molecular diagnostic tests for isoniazid-resistant #tuberculosis: a scoping review

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #TBSky #TB #AMR #OpenAccess #OA

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Congratulations to all of this year's honorees!

#TBSky #Tuberculosis

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Acceptability of a proposed new tuberculosis vaccine among people deprived of liberty in Brazil Tuberculosis (TB) persists as a global threat, with unequal burden across populations. New TB vaccines are in development, and people deprived of libe…

Happy to see that our work in TB vaccine acceptability in Brazilian prions is on!

6 male and 2 female prison units at 6 Brazilian cities, >900 individual interviews, with 95.2% of acceptance to a new proposed TB vaccine. However...

#TBsky #IDsky
www.sciencedirect.com/science/arti...

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TB Ed Talks
Dr. Jennifer Furin
with special guest Dr. Kelly Holland
Partnering with People: Compassion and the End of Tuberculosis
Celebrate Everything is Tuberculosis' birthday with a live presentation followed by Q&A
Wednesday, March 18th 8pm ET/5pm PT
on the TBFighters YouTube Channel

TB Ed Talks Dr. Jennifer Furin with special guest Dr. Kelly Holland Partnering with People: Compassion and the End of Tuberculosis Celebrate Everything is Tuberculosis' birthday with a live presentation followed by Q&A Wednesday, March 18th 8pm ET/5pm PT on the TBFighters YouTube Channel

Today is the anniversary of the publication of Everything is Tuberculosis! To celebrate, we’re sitting down with Dr. Jen Furin for her TB Ed Talk, Partnering with People: Compassion and the End of Tuberculosis. Join us this evening at 8 pm Eastern/5 pm Pacific on youtube!

#eitb #TBSky

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Register now to attend Dr. D J Christopher's talk on TB Elimination in India: The Challenges

ucsf.zoom.us/meeting/regi...

📅 March 19, 2026, at 8 am PDT

Hosted by the UCSF Institute for Global Health Sciences

#Tuberculosis #EndTB #TBSky

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March cover of The Lancet Microbe

March cover of The Lancet Microbe

Our March issue is now online:

www.thelancet.com/journals/lan...

Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #malaria #HIV #Streptococcus #PCV #RiftValleyFever #pertussis #tuberculosis #TB #AMR

#IDSky #ClinMicro #TBSky #OA

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New from AHRI in @jem.org AND on the cover!

📸 shows a human TB granuloma in lung tissue. The red, green & yellow cells shown, for example, are all different type of macrophage - immune cells that fight infection by engulfing & killing microbes like Mtb

#TBSky #IDSky

🔗 rupress.org/jem/article/...

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Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology Single-cell and spatial transcriptomics of human TB lung tissues from individuals in South Africa revealed that MMP1+CXCL5+ fibroblasts and SPP1+ macrophag

Played a small part in this cool study @jem.org.

Identifies myofibroblasts as sources of tissue damaging enzymes (MMP1) in TB granuloma, probably responding to cytokine cues from nearby macrophages.

Question now is: can we target therapeutically to prevent post-TB lung damage?

#TBSky #IDSky

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TBFighters are on the Hill today, advocating for increased funding to fight TB! Join us and help amplify our work by using @pih.org's tool to contact your representatives: https://act.pih.org/tb-funding-2026 
#TBHillDay #TBSky #IDSky

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El 18 de Marzo celebramos en Sevilla la IX Jornada de TB celebrando el día mundial de la TB. La inscripción es gratuita. Será presencial y on line simultáneamente. Os animamos a participar
#Tuberculosis #TBSky

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A great tool to be used in remote settings for countries having limited resources. Hoping for a quicker roll out now. #TBSky

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Unsurprising yet still depressing
#TBSky #IDSky

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🧪 Join us at the TB GAPS iECHOHub on Weds, 25 Feb for a presentation on Computer‑aided detection for pediatric TB, an emerging area of interest with unique diagnostic challenges and questions about performance, limitations, and appropriate use.
Register here: buff.ly/mIgT5ff
#GlobalHealth #TBSky

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