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Characterization of a novel Mycobacterium #tuberculosis serine protease Rv1815 in regulating bacterial metabolism & macrophage intracellular survival.

Rv1815, a serine protease of M. tuberculosis, shapes virulence, survival, metabolism & drug response
www.sciencedirect.com/science/arti... #MicroSky

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Complement activation on different clinical Mycobacterium tuberculosis complex (MTBC) strains in 10% serum. Clinical strains of 5 MTBC lineages were irradiated and incubated with 10% of normal human serum (NHS) that was preincubated with the different inhibitors and mock controls for 10 minutes at room temperature. Deposition of C3b (A) and membrane attack complex (MAC) formation (B) was measured by flow cytometry after incubation with specific monoclonal antibodies followed by the addition of fluorophore-labeled secondary antibodies. Median fluorescence intensity (MFI) values represent the level of complement activation after background subtraction, which was determined for each strain by negative controls that were processed identically but in the absence of 10% NHS. Data represent the mean ± SEM of 3 independent experiments.

Complement activation on different clinical Mycobacterium tuberculosis complex (MTBC) strains in 10% serum. Clinical strains of 5 MTBC lineages were irradiated and incubated with 10% of normal human serum (NHS) that was preincubated with the different inhibitors and mock controls for 10 minutes at room temperature. Deposition of C3b (A) and membrane attack complex (MAC) formation (B) was measured by flow cytometry after incubation with specific monoclonal antibodies followed by the addition of fluorophore-labeled secondary antibodies. Median fluorescence intensity (MFI) values represent the level of complement activation after background subtraction, which was determined for each strain by negative controls that were processed identically but in the absence of 10% NHS. Data represent the mean ± SEM of 3 independent experiments.

Novel insights into early host–pathogen dynamics of #tuberculosis emphasize the importance of considering Mycobacterium tuberculosis complex lineage diversity in understanding the immune response to mycobacterium. Read more: https://ow.ly/Srvj50Yyjkc

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Tuberculosis (TB) is a serious contagious disease caused by bacteria that typically affects the lungs but can also impact other parts of the body. TB spreads through the air when a person with active TB disease coughs, speaks, or sings.

buff.ly/l1MRQOB

#MED #TB #Tuberculosis

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Concerns With The BA 3 2 Covid Variant And Another Infectious Virus!
Concerns With The BA 3 2 Covid Variant And Another Infectious Virus! YouTube video by Data Report

Concerns With The BA 3 2 Covid Variant And Another Infectious Virus!

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=6zw1...

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Eliminating Tuberculosis with the Search, Treat, and Prevent Approach for All At Partners In Health, this approach guides our TB ambitions around the world.

✍🏻🔎”The universal access search, treat, and prevent approach is an important part of stopping unnecessary deaths from #tuberculosis …Roughly every 20 seconds, someone dies from TB. Most of those deaths are in low-and middle-income countries, such as ones where PIH works; however, TB is everywhere…”

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🔬 BreathForDx at #AMCLI2026

The BreathForDx project and the use of face masks for XBA collection were presented during the 53rd National AMCLI Congress in Rimini, Italy.

Presentation by Dr. Francesca Saluzzo, moderated by Prof. Daniela Maria Cirillo.

#BreathForDx #Tuberculosis #Diagnostics

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See Which Highly Populated Wastewater Site Is Seeing A Big Covid Surge
See Which Highly Populated Wastewater Site Is Seeing A Big Covid Surge YouTube video by Data Report

See Which Highly Populated Wastewater Site Is Seeing A Big Covid Surge

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=bePN...

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Once Called the “White Death,” Tuberculosis Lingers as Trends Shift in the U.S. and Globally #Science #HealthandMedicine #InfectiousDiseases #Tuberculosis #PublicHealth

www.discovermagazine.com/once-called-the-white-de...

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‘White plague’ is on the rise in the US — it’s deadlier than COVID and becoming antibiotic-resistant One of humanity’s oldest and deadliest killers is staging a modern-day comeback.

‘White plague’ is on the rise in the United States ...

| #TB | #infections | #pathogen | #tuberculosis | #Mycobacterium | #microbiology | #bacteria | Via @nypost.com

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Tuberculosis research principles and priorities in children and adolescents: an international consensus statement Each year, an estimated 1·9 million children (aged 0–9 years) and adolescents (aged 10–19 years) develop tuberculosis disease. Tuberculosis ranks among the top ten causes of death in children younger ...

#Tuberculosis research principles and priorities in children and adolescents: an international consensus statement www.thelancet.com/journals/lan... (free access with website registration)

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A Longitudinal, Observational Study of Etiology and Long-Term Outcomes of Sepsis in Malawi Revealing the Key Role of Disseminated Tuberculosis - PubMed Sepsis in Blantyre, Malawi, is caused by a range of pathogens; the majority are not susceptible to the broad-spectrum antibacterials that most patients receive. HIV status is a key determinant of etiology. Novel antimicrobial strategies for sepsis tailored to sub-Saharan Africa, including considerat …

At least 34% of adults with sepsis in Malawi have #tuberculosis pubmed.ncbi.nlm.nih.gov/34407175/

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Aetiology of sepsis in adults living with HIV in East Africa: a secondary analysis of an open-label, multicentre, randomised, controlled phase 3 trial Mtb was the most common pathogen causing sepsis and bloodstream infection and was frequently missed by conventional rapid diagnostics. We also identified a high prevalence of non-mycobacterial pathoge...

The Aetiology of Sepsis in Adults Living with HIV in East Africa. 52% had #tuberculosis

www.thelancet.com/journals/ecl...

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Sepsis Sepsis is defined as a dysregulated host response to infection that leads to life-threatening organ dysfunction. The infectious insult triggers a dysregulated immune response that variably activates a...

The commonest cause of sepsis in adults with advanced HIV disease in Africa didn't even get a mention! @thelancet.com #tuberculosis Sepsis - The Lancet www.thelancet.com/journals/lan...

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Misinformation About Covid And Other Viruses Is Deadly.
Misinformation About Covid And Other Viruses Is Deadly. YouTube video by Data Report

Misinformation About Covid And Other Viruses Is Deadly.

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=UM8c...

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The Curry International Tuberculosis Center is pleased to announce the availability of the following archived webinar:

The Evolving Landscape of Laboratory Testing for Tuberculosis

www.currytbcenter.ucsf.edu/trainings/ar...

#Tuberculosis #TBSky @aphl.org #GotCurry #CurryTBCenter

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New #IJID editorial: Scientific advances in TB are accelerating, but global impact is not keeping pace. The challenge is no longer innovation—it is implementation.

🔗 Read more: https://ow.ly/3IJS50YzsyM

#WorldTBDay #EndTBwithISID #Tuberculosis #ISID

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WHO recommends new diagnostic tools to help end TB On World TB Day, the World Health Organization (WHO) is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as …

#WHO recommends new #diagnostic tools to help end #TB ...

| #tuberculosis | #Mycobacterium | #tongue | #swab | Via @who.int

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🔬 Nueva publicación: caso en Panamá evidencia el impacto del diagnóstico tardío de tuberculosis en embarazo y su transmisión vertical.

DOI: 10.22541/au.176218214.45472959/v1
#Tuberculosis #INDICASATAIP

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So TB is back in a big way in the US — 10,388 cases last year, highest since 2011. Four straight years of increases after decades of decline. The mix is rough: reactivated latent infections, outbreaks in shelters and prisons, and federal funding getting slashed right when we need it most. 2025 numbers look even worse. We were supposed to be eliminating this disease, not watching it rebound.

https://crowdbyte.ai/topics/deadly-infectious-disease-rebounds-in-us-after-eradication-hopes

So TB is back in a big way in the US — 10,388 cases last year, highest since 2011. Four straight years of increases after decades of decline. The mix is rough: reactivated latent infections, outbreaks in shelters and prisons, and federal funding getting slashed right when we need it most. 2025 numbers look even worse. We were supposed to be eliminating this disease, not watching it rebound. https://crowdbyte.ai/topics/deadly-infectious-disease-rebounds-in-us-after-eradication-hopes

#Tuberculosis ! "So TB is back in a big way in the US—10,388 cases last year.... The mix is rough: reactivated latent infections, outbreaks in shelters and prisons, and federal funding getting slashed right when we need it most."
crowdbyte.ai/topics/deadl...
www.threads.com/@crowd_byte/...

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A red card on a black background with the words "History in Santa Fe New Mexico". Inside the letters of Santa Fe are different photos of a statue, a chile ristra, a chile pepper, an old photo, and other Santa Fe emblems.

A red card on a black background with the words "History in Santa Fe New Mexico". Inside the letters of Santa Fe are different photos of a statue, a chile ristra, a chile pepper, an old photo, and other Santa Fe emblems.

New Mexico’s First Art Colony & the #TaosModerns

#MainLibrary Community Room
Thursday, April 2, 2026
3:00–4:00pm

Register here: www.santafelibrary.org/event/ana-pa...

The scourge of #tuberculosis during the latter part of the 19th century brought many creative people chasing the cure to Santa Fe.

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Design and characterization of #HIV-1 #vaccine candidates to elicit antibodies targeting multiple epitopes. From Gristick, @bjorkman-lab.bsky.social et al.: rupress.org/jem/article/...

📘 Updates on the Immune Responses to #Tuberculosis & #HIV rupress.org/jem/collecti...
#KSTB26 #KSHIVVax26

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WHO recommends new diagnostic tools to help end TB On World TB Day, the World Health Organization (WHO) is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as diagnostic tests that can be used near the point-of-care and tongue swabs that can help detect the disease faster reaching more people.

Over 3,300 people die from #tuberculosis every day.

New @who.int-recommended diagnostic tools could bring faster, cheaper testing closer to patients and help close critical detection gaps.

🟠 https://tinyurl.com/yvbraakv

#WorldTBDay #GlobalHealth #EndTB

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If this continues, thousands of deaths in the coming years could still be prevented.

Closing this gap means accelerating efforts - from detection and diagnosis to treatment and follow-up.

Read more here: bit.ly/WorldTBDay2026

#WorldTBDay #Tuberculosis #PublicHealth #ECDC #EUHealth

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Tuberculosis in Europe: progress - but not fast enough.

While rates have declined over time, current trends show we are not on track to meet the 2030 global tuberculosis targets.

#TB #Tuberculosis #IDsky #EpiSky #MedSky

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La #tuberculosis marca 206 defunciones, frente a 3400 altas hospitalarias🫁
🔸69% defunciones de hombres♂️
🔸31% de mujeres♀️

#InfografiasINE @es-ine.bsky.social
👇
ine.es/infografias/...

#Defunciones según causa de muerte➡️ ine.es/dyngs/INEbas...

#Morbilidad hospitalaria➡️ ine.es/dyngs/INEbas...
#INE

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Common misconceptions of tuberculosis pt. 2

🩺 On Monday, we spoke to @nickherbert.com about tuberculosis, what people may not understand about it, and what we can do to stop the world's deadliest disease.

#Tuberculosis #EndTB #YesWeCanEndTB

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That small scar tells a big story about protection against tuberculosis.

And today, protection continues even if you can’t always see it. 🛡️💉

🔗 bit.ly/WorldTBDay2026
#WorldTBday #Tuberculosis #TB #PublicHealth

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Is The Rumor You May Have Heard About A New Covid Variant True?
Is The Rumor You May Have Heard About A New Covid Variant True? YouTube video by Data Report

Is The Rumor You May Have Heard About A New Covid Variant True?

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=ItHn...

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Tuberculosis remains the world’s deadliest infectious disease – Australia’s regional leadership matters Tuberculosis is preventable and curable, yet remains the world’s deadliest infectious disease. Australia’s regional role is critical to changing that.

Tuberculosis is preventable and curable – yet it remains the world’s deadliest infectious disease.
Australia must step up regional investment and leadership to tackle TB in the Indo-Pacific, Kate Thwaites and Dr Sophie Scamps write.
#auspol #globalhealth #tuberculosis #IndoPacific

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Structural and genetic basis of #HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies. From Roark, Habib, Shaw, Kwong, Shapiro et al.: rupress.org/jem/article/...

📘 Updates on the Immune Responses to #Tuberculosis & #HIV rupress.org/jem/collecti...
#KSTB26 #KSHIVVax26

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